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10.1084/jem.20142224

http://scihub22266oqcxt.onion/10.1084/jem.20142224
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C4451131!4451131!25964370
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suck abstract from ncbi


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pmid25964370      J+Exp+Med 2015 ; 212 (6): 875-82
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  • Bcl11b is essential for group 2 innate lymphoid cell development #MMPMID25964370
  • Walker JA; Oliphant CJ; Englezakis A; Yu Y; Clare S; Rodewald HR; Belz G; Liu P; Fallon PG; McKenzie AN
  • J Exp Med 2015[Jun]; 212 (6): 875-82 PMID25964370show ga
  • Walker et al. demonstrate that the transcription factor Bcl11b is expressed in mouse lymphoid ILC2 precursors in the bone marrow and is required for their development. Mice deficient in Bcl11b exhibit a lack of ILC2 development and an expansion of ROR?t+ ILC3s and are unable to clear Nippostrongylus brasiliensis worm infection, but can clear Citrobacter rodentium.
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