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10.1038/nsmb.2931 http://scihub22266oqcxt.onion/10.1038/nsmb.2931 C4450863!4450863!25565029     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25565029&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Struct+Mol+Biol 2015 ; 22 (1): 20-8 Nephropedia Template TP {{tp|p=25565029|t=2015. From Guide to Target: Molecular Insights into Eukaryotic RNAi Machinery |pdf=|usr=}}{{25565029}} gab.com Text From Guide to Target: Molecular Insights into Eukaryotic RNAi Machinery JO: Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=25565029 #FOAvip Since its relatively recent discovery, RNA interference (RNAi) has emerged as a potent, specific, and ubiquitous means of gene regulation. Through a number of pathways that are conserved from yeast to humans, small non-coding RNAs direct molecular machinery to silence gene expression. In this review, we focus on mechanisms and structures that govern RNA silencing in higher organisms. In addition to highlighting recent advances, parallels and differences between RNAi pathways are discussed. Together, the studies reviewed herein reveal the versatility and programmability of RNA-induced Silencing Complexes (RISCs) and emphasize the importance of both upstream biogenesis and downstream silencing factors. Twit Text FOAVip From Guide to Target: Molecular Insights into Eukaryotic RNAi Machinery ????Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=25565029 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25565029 #FOAvip English Wikipedia <ref>{{Cite pmid|25565029}}</ref> From Guide to Target: Molecular Insights into Eukaryotic RNAi Machinery #MMPMID25565029 Ipsaro JJ; Joshua-Tor L Nat Struct Mol Biol 2015[Jan]; 22 (1): 20-8 PMID25565029show ga Since its relatively recent discovery, RNA interference (RNAi) has emerged as a potent, specific, and ubiquitous means of gene regulation. Through a number of pathways that are conserved from yeast to humans, small non-coding RNAs direct molecular machinery to silence gene expression. In this review, we focus on mechanisms and structures that govern RNA silencing in higher organisms. In addition to highlighting recent advances, parallels and differences between RNAi pathways are discussed. Together, the studies reviewed herein reveal the versatility and programmability of RNA-induced Silencing Complexes (RISCs) and emphasize the importance of both upstream biogenesis and downstream silencing factors. äFrom Guide to Target: Molecular Insights into Eukaryotic RNAi Machiner(epmc).pdf DeepDyve Pubget Overpricing