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2014 ; 120
(4
): 864-72
Nephropedia Template TP
gab.com Text
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English Wikipedia
Hockey Concussion Education Project, Part 1 Susceptibility-weighted imaging
study in male and female ice hockey players over a single season
#MMPMID24490839
Helmer KG
; Pasternak O
; Fredman E
; Preciado RI
; Koerte IK
; Sasaki T
; Mayinger M
; Johnson AM
; Holmes JD
; Forwell LA
; Skopelja EN
; Shenton ME
; Echlin PS
J Neurosurg
2014[Apr]; 120
(4
): 864-72
PMID24490839
show ga
OBJECT: Concussion, or mild traumatic brain injury (mTBI), is a commonly
occurring sports-related injury, especially in contact sports such as hockey.
Cerebral microbleeds (CMBs), which appear as small, hypointense lesions on
T?*-weighted images, can result from TBI. The authors use susceptibility-weighted
imaging (SWI) to automatically detect small hypointensities that may be subtle
signs of chronic and acute damage due to both subconcussive and concussive
injury. The goal was to investigate how the burden of these hypointensities
changes over time, over a playing season, and postconcussion, in comparison with
subjects who did not suffer a medically observed and diagnosed concussion.
METHODS: Images were obtained in 45 university-level adult male and female ice
hockey players before and after a single Canadian Interuniversity Sports season.
In addition, 11 subjects (5 men and 6 women) underwent imaging at 72 hours, 2
weeks, and 2 months after concussion. To identify subtle changes in brain tissue
and potential CMBs, nonvessel clusters of hypointensities on SWI were
automatically identified, and a hypointensity burden index was calculated for all
subjects at the beginning of the season (BOS), the end of the season (EOS), and
at postconcussion time points (where applicable). RESULTS: A statistically
significant increase in the hypointensity burden, relative to the BOS, was
observed for male subjects with concussions at the 2-week postconcussion time
point. A smaller, nonsignificant rise in the burden for female subjects with
concussions was also observed within the same time period. There were no
significant changes in burden for nonconcussed subjects of either sex between the
BOS and EOS time points. However, there was a statistically significant
difference in the burden between male and female subjects in the nonconcussed
group at both the BOS and EOS time points, with males having a higher burden.
CONCLUSIONS: This method extends the utility of SWI from the enhancement and
detection of larger (> 5 mm) CMBs, which are often observed in more severe cases
of TBI, to cases involving smaller lesions in which visual detection of injury is
difficult. The hypointensity burden metric proposed here shows statistically
significant changes over time in the male subjects. A smaller, nonsignificant
increase in the burden metric was observed in the female subjects.