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10.1155/2015/476534

http://scihub22266oqcxt.onion/10.1155/2015/476534
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C4450229!4450229!26120582
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suck abstract from ncbi


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pmid26120582      Biomed+Res+Int 2015 ; 2015 (ä): ä
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  • Strategies of Intracellular Pathogens for Obtaining Iron from the Environment #MMPMID26120582
  • Leon-Sicairos N; Reyes-Cortes R; Guadrón-Llanos AM; Madueña-Molina J; Leon-Sicairos C; Canizalez-Román A
  • Biomed Res Int 2015[]; 2015 (ä): ä PMID26120582show ga
  • Most microorganisms are destroyed by the host tissues through processes that usually involve phagocytosis and lysosomal disruption. However, some organisms, called intracellular pathogens, are capable of avoiding destruction by growing inside macrophages or other cells. During infection with intracellular pathogenic microorganisms, the element iron is required by both the host cell and the pathogen that inhabits the host cell. This minireview focuses on how intracellular pathogens use multiple strategies to obtain nutritional iron from the intracellular environment in order to use this element for replication. Additionally, the implications of these mechanisms for iron acquisition in the pathogen-host relationship are discussed.
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