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10.3390/jcm3020480 http://scihub22266oqcxt.onion/10.3390/jcm3020480 C4449679!4449679!26237386     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med 2014 ; 3 (2): 480-90 Nephropedia Template TP {{tp|p=26237386|t=2014. First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus |pdf=|usr=}}{{26237386}} gab.com Text First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=26237386 #FOAvip Objective: To investigate whether maternal serum pregnancy associated plasma protein-A (PAPP-A), total ? human chorionic gonadotropin (hCG) levels and nuchal translucency (NT) measurements differ in women with pre-gestational diabetes mellitus (PGDM) compared to non-diabetic controls and to assess whether correction factors are needed for diabetic women in calculation of aneuploidy risks. Study Design: We performed a retrospective study of all women who underwent first trimester aneuploidy screening (11 + 0 to 13 + 6 weeks) from 2005 to 2011. The primary study outcome was the difference in PAPP-A, ?-hCG and NT multiples of median between women with PGDM and non-diabetic women. Results: Of 6741 eligible patients, 103 patients with PGDM were using insulin and 4 patients were using oral hypoglycemic agents; the latter were excluded due to small number. There was 12% reduction of median PAPP-A (p = 0.001) and 18% reduction of median hCG (p = 0.006) in women with PGDM receiving insulin. There was no difference in NT. Conclusions: In women with PGDM receiving insulin, PAPP-A and ?-hCG levels are significantly lower compared to non-diabetic women. This suggests that when calculating risks for aneuploidy, correction factors should be considered to adjust PAPP-A and ?-hCG concentrations to those seen in non-diabetic women. Twit Text FOAVip First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=26237386 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26237386 #FOAvip English Wikipedia <ref>{{Cite pmid|26237386}}</ref> First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus #MMPMID26237386 Gurram P; Benn P; Grady J; Prabulos AM; Campbell W J Clin Med 2014[Jun]; 3 (2): 480-90 PMID26237386show ga Objective: To investigate whether maternal serum pregnancy associated plasma protein-A (PAPP-A), total ? human chorionic gonadotropin (hCG) levels and nuchal translucency (NT) measurements differ in women with pre-gestational diabetes mellitus (PGDM) compared to non-diabetic controls and to assess whether correction factors are needed for diabetic women in calculation of aneuploidy risks. Study Design: We performed a retrospective study of all women who underwent first trimester aneuploidy screening (11 + 0 to 13 + 6 weeks) from 2005 to 2011. The primary study outcome was the difference in PAPP-A, ?-hCG and NT multiples of median between women with PGDM and non-diabetic women. Results: Of 6741 eligible patients, 103 patients with PGDM were using insulin and 4 patients were using oral hypoglycemic agents; the latter were excluded due to small number. There was 12% reduction of median PAPP-A (p = 0.001) and 18% reduction of median hCG (p = 0.006) in women with PGDM receiving insulin. There was no difference in NT. Conclusions: In women with PGDM receiving insulin, PAPP-A and ?-hCG levels are significantly lower compared to non-diabetic women. This suggests that when calculating risks for aneuploidy, correction factors should be considered to adjust PAPP-A and ?-hCG concentrations to those seen in non-diabetic women. äFirst Trimester Aneuploidy Screening Markers in Women with Pre-Gestati(epmc).pdf DeepDyve Pubget Overpricing