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10.1182/blood-2014-09-600411

http://scihub22266oqcxt.onion/10.1182/blood-2014-09-600411
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C4449039!4449039!25833956
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suck abstract from ncbi


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pmid25833956      Blood 2015 ; 125 (21): 3253-62
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  • Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS #MMPMID25833956
  • Cofiell R; Kukreja A; Bedard K; Yan Y; Mickle AP; Ogawa M; Bedrosian CL; Faas SJ
  • Blood 2015[May]; 125 (21): 3253-62 PMID25833956show ga
  • This exploratory study describes the effect of eculizumab on multiple physiologic pathways affected by complement dysregulation in aHUS.The results highlight the importance of sustained terminal complement blockade, even in patients with improved clinical laboratory values.
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