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10.1101/cshperspect.a017996 http://scihub22266oqcxt.onion/10.1101/cshperspect.a017996 C4448608!4448608!26032716     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cold+Spring+Harb+Perspect+Biol 2015 ; 7 (6): ä Nephropedia Template TP {{tp|p=26032716|t=2015. Evolution of New Functions De Novo and from Preexisting Genes |pdf=|usr=}}{{26032716}} gab.com Text Evolution of New Functions De Novo and from Preexisting Genes JO: Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=26032716 #FOAvip How the enormous structural and functional diversity of new genes and proteins was generated (estimated to be 1010?1012 different proteins in all organisms on earth [Choi I-G, Kim S-H. 2006. Evolution of protein structural classes and protein sequence families. Proc Natl Acad Sci103: 14056?14061] is a central biological question that has a long and rich history. Extensive work during the last 80 years have shown that new genes that play important roles in lineage-specific phenotypes and adaptation can originate through a multitude of different mechanisms, including duplication, lateral gene transfer, gene fusion/fission, and de novo origination. In this review, we focus on two main processes as generators of new functions: evolution of new genes by duplication and divergence of pre-existing genes and de novo gene origination in which a whole protein-coding gene evolves from a noncoding sequence. Twit Text FOAVip Evolution of New Functions De Novo and from Preexisting Genes ????Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=26032716 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26032716 #FOAvip English Wikipedia <ref>{{Cite pmid|26032716}}</ref> Evolution of New Functions De Novo and from Preexisting Genes #MMPMID26032716 Andersson DI; Jerlström-Hultqvist J; Näsvall J Cold Spring Harb Perspect Biol 2015[Jun]; 7 (6): ä PMID26032716show ga How the enormous structural and functional diversity of new genes and proteins was generated (estimated to be 1010?1012 different proteins in all organisms on earth [Choi I-G, Kim S-H. 2006. Evolution of protein structural classes and protein sequence families. Proc Natl Acad Sci103: 14056?14061] is a central biological question that has a long and rich history. Extensive work during the last 80 years have shown that new genes that play important roles in lineage-specific phenotypes and adaptation can originate through a multitude of different mechanisms, including duplication, lateral gene transfer, gene fusion/fission, and de novo origination. In this review, we focus on two main processes as generators of new functions: evolution of new genes by duplication and divergence of pre-existing genes and de novo gene origination in which a whole protein-coding gene evolves from a noncoding sequence. äEvolution of New Functions De Novo and from Preexisting Genes (epmc).pdf DeepDyve Pubget Overpricing