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10.1101/cshperspect.a022392

http://scihub22266oqcxt.onion/10.1101/cshperspect.a022392
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C4448581!4448581!25934463
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suck abstract from ncbi

pmid25934463      Cold+Spring+Harb+Perspect+Med 2015 ; 5 (5): ä
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  • Malformations of Cortical Development and Epilepsy #MMPMID25934463
  • Barkovich AJ; Dobyns WB; Guerrini R
  • Cold Spring Harb Perspect Med 2015[May]; 5 (5): ä PMID25934463show ga
  • Malformations of cortical development (MCDs) are an important cause of epilepsy and an extremely interesting group of disorders from the perspective of brain development and its perturbations. Many new MCDs have been described in recent years as a result of improvements in imaging, genetic testing, and understanding of the effects of mutations on the ability of their protein products to correctly function within the molecular pathways by which the brain functions. In this review, most of the major MCDs are reviewed from a clinical, embryological, and genetic perspective. The most recent literature regarding clinical diagnosis, mechanisms of development, and future paths of research are discussed.
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