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http://scihub22266oqcxt.onion/ C4448200!4448200!26045900     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transl+Res 2015 ; 7 (3): 616-23 Nephropedia Template TP {{tp|p=26045900|t=2015. Knockdown of YEATS4 inhibits colorectal cancer cell proliferation and induces apoptosis |pdf=|usr=}}{{26045900}} gab.com Text Knockdown of YEATS4 inhibits colorectal cancer cell proliferation and induces apoptosis JO: Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26045900 #FOAvip YEATS domain containing 4 (YEATS4) is usually amplified and functions as an oncogene in human glioma. However, the biological role of YEATS4 in colorectal cancer (CRC) has not yet been discussed. In this study, we investigated the expression level of YEATS4 in 85 pairs of CRC and paracancerous tissues, and knocked down YEATS4 via a lentivirus system in RKO CRC cell line. Although YEATS4 was upregulated in CRC tissues, YEATS4 expression showed no association with any clinical features and overall survival. Inhibition of YEATS4 significantly suppressed cell proliferation and colony formation. Flow cytometry revealed that cell cycle was arrested in the G0/G1 phase and the number of apoptotic cells were significantly increased when YEATS4 expression was inhibited. In conclusion, our findings provide first evidence that YEATS4 may be an important regulator of cell proliferation and apoptosis in CRC cells. Twit Text FOAVip Knockdown of YEATS4 inhibits colorectal cancer cell proliferation and induces apoptosis ????Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26045900 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26045900 #FOAvip English Wikipedia <ref>{{Cite pmid|26045900}}</ref> Knockdown of YEATS4 inhibits colorectal cancer cell proliferation and induces apoptosis #MMPMID26045900 Tao K; Yang J; Hu Y; Deng A Am J Transl Res 2015[]; 7 (3): 616-23 PMID26045900show ga YEATS domain containing 4 (YEATS4) is usually amplified and functions as an oncogene in human glioma. However, the biological role of YEATS4 in colorectal cancer (CRC) has not yet been discussed. In this study, we investigated the expression level of YEATS4 in 85 pairs of CRC and paracancerous tissues, and knocked down YEATS4 via a lentivirus system in RKO CRC cell line. Although YEATS4 was upregulated in CRC tissues, YEATS4 expression showed no association with any clinical features and overall survival. Inhibition of YEATS4 significantly suppressed cell proliferation and colony formation. Flow cytometry revealed that cell cycle was arrested in the G0/G1 phase and the number of apoptotic cells were significantly increased when YEATS4 expression was inhibited. In conclusion, our findings provide first evidence that YEATS4 may be an important regulator of cell proliferation and apoptosis in CRC cells. äKnockdown of YEATS4 inhibits colorectal cancer cell proliferation and (epmc).pdf DeepDyve Pubget Overpricing