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10.12703/P7-66 http://scihub22266oqcxt.onion/10.12703/P7-66 C4447035!4447035!26097739     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       F1000Prime+Rep 2015 ; 7 (ä): ä Nephropedia Template TP {{tp|p=26097739|t=2015. Hematopoietic transcription factor mutations and inherited platelet dysfunction |pdf=|usr=}}{{26097739}} gab.com Text Hematopoietic transcription factor mutations and inherited platelet dysfunction JO: F1000Prime Rep http://www.kidney.de/pget.php?&tw=1&pmid=26097739 #FOAvip The molecular and genetic mechanisms in most patients with inherited platelet dysfunction are unknown. There is increasing evidence that mutations in hematopoietic transcription factors are major players in the pathogenesis of defective megakaryopoiesis and platelet dysfunction in patients with inherited platelet disorders. These hematopoietic transcription factors include RUNX1, FLI1, GATA-1, and GFI1B. Mutations involving these transcription factors affect diverse aspects of platelet production and function at the genetic and molecular levels, culminating in clinical manifestations of thrombocytopenia and platelet dysfunction. This review focuses on these hematopoietic transcription factors in the pathobiology of inherited platelet dysfunction. Twit Text FOAVip Hematopoietic transcription factor mutations and inherited platelet dysfunction ????F1000Prime Rep http://www.kidney.de/pget.php?&tw=1&pmid=26097739 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26097739 #FOAvip English Wikipedia <ref>{{Cite pmid|26097739}}</ref> Hematopoietic transcription factor mutations and inherited platelet dysfunction #MMPMID26097739 Songdej N; Rao AK F1000Prime Rep 2015[]; 7 (ä): ä PMID26097739show ga The molecular and genetic mechanisms in most patients with inherited platelet dysfunction are unknown. There is increasing evidence that mutations in hematopoietic transcription factors are major players in the pathogenesis of defective megakaryopoiesis and platelet dysfunction in patients with inherited platelet disorders. These hematopoietic transcription factors include RUNX1, FLI1, GATA-1, and GFI1B. Mutations involving these transcription factors affect diverse aspects of platelet production and function at the genetic and molecular levels, culminating in clinical manifestations of thrombocytopenia and platelet dysfunction. This review focuses on these hematopoietic transcription factors in the pathobiology of inherited platelet dysfunction. äHematopoietic transcription factor mutations and inherited platelet dy(epmc).pdf DeepDyve Pubget Overpricing