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10.1038/srep10504 http://scihub22266oqcxt.onion/10.1038/srep10504 C4444851!4444851!26015263     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26015263|t=2015. Cell Size Modulates Oscillation, Positioning and Length of Mitotic Spindles |pdf=|usr=}}{{26015263}} gab.com Text Cell Size Modulates Oscillation, Positioning and Length of Mitotic Spindles JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26015263 #FOAvip Mitotic spindle is the main subcellular structure that accomplishes the chromosome segregation between daughter cells during cell division. However, how mitotic spindles sense and control their size, position and movement inside the cell still remains unclear. In this paper, we focus on the size effects of mitotic spindles, i.e., how cell size controls various interesting phenomena in the metaphase, such as oscillation, positioning and size limit of mitotic spindles. We systematically studied the frequency doubling phenomenon during chromosome oscillation and found that cell size can regulate the period and amplitude of chromosome oscillation. We found that the relaxation time of the positioning process increases exponentially with cell size. We also showed that the stabler microtubule-kinetochore attachments alone can directly lead to an upper limit of spindle size. Our work not only explains the existing experimental observations, but also provides some interesting predictions that can be verified or rejected by further experiments. Twit Text FOAVip Cell Size Modulates Oscillation, Positioning and Length of Mitotic Spindles ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26015263 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26015263 #FOAvip English Wikipedia <ref>{{Cite pmid|26015263}}</ref> Cell Size Modulates Oscillation, Positioning and Length of Mitotic Spindles #MMPMID26015263 Jiang H Sci Rep 2015[]; 5 (ä): ä PMID26015263show ga Mitotic spindle is the main subcellular structure that accomplishes the chromosome segregation between daughter cells during cell division. However, how mitotic spindles sense and control their size, position and movement inside the cell still remains unclear. In this paper, we focus on the size effects of mitotic spindles, i.e., how cell size controls various interesting phenomena in the metaphase, such as oscillation, positioning and size limit of mitotic spindles. We systematically studied the frequency doubling phenomenon during chromosome oscillation and found that cell size can regulate the period and amplitude of chromosome oscillation. We found that the relaxation time of the positioning process increases exponentially with cell size. We also showed that the stabler microtubule-kinetochore attachments alone can directly lead to an upper limit of spindle size. Our work not only explains the existing experimental observations, but also provides some interesting predictions that can be verified or rejected by further experiments. äCell Size Modulates Oscillation, Positioning and Length of Mitotic Spi(epmc).pdf DeepDyve Pubget Overpricing