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10.1161/CIRCRESAHA.116.306374 http://scihub22266oqcxt.onion/10.1161/CIRCRESAHA.116.306374 C4443843!4443843!25999423     free     free     free       Circ+Res 2015 ; 116 (11): 1835-49 Nephropedia Template TP {{tp|p=25999423|t=2015. How mitochondrial dynamism orchestrates mitophagy |pdf=|usr=}}{{25999423}} gab.com Text How mitochondrial dynamism orchestrates mitophagy JO: Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=25999423 #FOAvip Mitochondria are highly dynamic, except in adult cardiomyocytes. Yet, the fission and fusion-promoting proteins that mediate mitochondrial dynamism are highly expressed in, and essential to the normal functioning of, hearts. Here, we review accumulating evidence supporting important roles for mitochondrial fission and fusion in cardiac mitochondrial quality control, focusing on the PINK1-Parkin mitophagy pathway.Based in part on recent findings from in vivo mouse models in which mitofusin-mediated mitochondrial fusion or Drp1-mediated mitochondrial fission were conditionally interrupted in cardiac myocytes, we propose several new concepts that may provide insight into the cardiac mitochondrial dynamism-mitophagy interactome. Twit Text FOAVip How mitochondrial dynamism orchestrates mitophagy ????Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=25999423 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25999423 #FOAvip English Wikipedia <ref>{{Cite pmid|25999423}}</ref> How mitochondrial dynamism orchestrates mitophagy #MMPMID25999423 Shirihai O; Song M; Dorn GW Circ Res 2015[May]; 116 (11): 1835-49 PMID25999423show ga Mitochondria are highly dynamic, except in adult cardiomyocytes. Yet, the fission and fusion-promoting proteins that mediate mitochondrial dynamism are highly expressed in, and essential to the normal functioning of, hearts. Here, we review accumulating evidence supporting important roles for mitochondrial fission and fusion in cardiac mitochondrial quality control, focusing on the PINK1-Parkin mitophagy pathway.Based in part on recent findings from in vivo mouse models in which mitofusin-mediated mitochondrial fusion or Drp1-mediated mitochondrial fission were conditionally interrupted in cardiac myocytes, we propose several new concepts that may provide insight into the cardiac mitochondrial dynamism-mitophagy interactome. äHow mitochondrial dynamism orchestrates mitophagy (epmc).pdf DeepDyve Pubget Overpricing