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2015 ; 5
(Suppl 1
): S49-53
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Hepatic encephalopathy and sleepiness: an interesting connection?
#MMPMID26041958
Montagnese S
; Turco M
; Amodio P
J Clin Exp Hepatol
2015[Mar]; 5
(Suppl 1
): S49-53
PMID26041958
show ga
Sleep-wake abnormalities in patients with cirrhosis have been traditionally
associated with hepatic encephalopathy (HE). In recent years, a certain amount of
work has been devoted to the study of this relationship. This has lead to a
modified picture, with weakening of the association between HE and poor night
sleep, and the emergence of stronger links between HE and excessive daytime
sleepiness. This brief review focuses on the evidence in favor of the
interpretation of HE as a sleepiness syndrome, and on the diagnostic, therapeutic
and social implications of such an interpretation.