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10.1085/jgp.201411332

http://scihub22266oqcxt.onion/10.1085/jgp.201411332
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C4442790!4442790!26009547
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suck abstract from ncbi

pmid26009547      J+Gen+Physiol 2015 ; 145 (6): 565-74
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  • The Hill analysis and co-ion?driven transporter kinetics #MMPMID26009547
  • Lolkema JS; Slotboom DJ
  • J Gen Physiol 2015[Jun]; 145 (6): 565-74 PMID26009547show ga
  • Interaction of multiple ligands with a protein or protein complex is a widespread phenomenon that allows for cooperativity. Here, we review the use of the Hill equation, which is commonly used to analyze binding or kinetic data, to analyze the kinetics of ion-coupled transporters and show how the mechanism of transport affects the Hill coefficient. Importantly, the Hill analysis of ion-coupled transporters can provide the exact number of transported co-ions, regardless of the extent of the cooperativity in ion binding.
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