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10.1093/ckj/sft063 http://scihub22266oqcxt.onion/10.1093/ckj/sft063 C4438390!4438390!26064510     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Kidney+J 2013 ; 6 (5): 469-72 Nephropedia Template TP {{tp|p=26064510|t=2013. Minimal-change disease in adolescents and adults: epidemiology and therapeutic response |pdf=|usr=}}{{26064510}} gab.com Text Minimal-change disease in adolescents and adults: epidemiology and therapeutic response JO: Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=26064510 #FOAvip Background: Epidemiology of minimal-change disease (MCD) in adults differs from that in children and is not studied well in Indian population. Methods: We retrospectively studied the records of 61 adult patients with MCD to assess clinical, laboratory and histopathological features, and to evaluate the response to treatment, course and complications of the disease and therapy. Results: The male to female ratio was 1.17:1. Mean age was 30.46 years. Of the total, 6.55% had hypertension; 13.11% had microhaematuria. After initial treatment with steroids, 68.85% had complete remission (CR) and 13.1% had partial remission (PR). Twelve of 14 (85.71%) steroid-resistant cases had CR or PR after alternative immunosuppression with cyclophosphamide, or mycophenolate mofetil. Of all patients, 44.2% had at least one relapse; 8.19% were frequently relapsing and 26.22% were steroid dependent. After a mean follow-up of 149.9 weeks, 38 (61.29%) patients were in CR and 16 (26.22%) in PR with a mean proteinuria of 1.28 g/day, 3 being treated for relapse. Mean serum creatinine was 89.28 ?mol/L (1.01 mg/dL). Fourteen (22.95%) had acute kidney injury (AKI). All but two recovered completely. Conclusions: This single-centre study with a medium-term follow-up shows that majority of patients respond to steroids or alternative immunosuppressants. AKI is common and may not be completely reversible in some cases. Twit Text FOAVip Minimal-change disease in adolescents and adults: epidemiology and therapeutic response ????Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=26064510 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26064510 #FOAvip English Wikipedia <ref>{{Cite pmid|26064510}}</ref> Minimal-change disease in adolescents and adults: epidemiology and therapeutic response #MMPMID26064510 Keskar V; Jamale TE; Kulkarni MJ; Kiggal Jagadish P; Fernandes G; Hase N Clin Kidney J 2013[Oct]; 6 (5): 469-72 PMID26064510show ga Background: Epidemiology of minimal-change disease (MCD) in adults differs from that in children and is not studied well in Indian population. Methods: We retrospectively studied the records of 61 adult patients with MCD to assess clinical, laboratory and histopathological features, and to evaluate the response to treatment, course and complications of the disease and therapy. Results: The male to female ratio was 1.17:1. Mean age was 30.46 years. Of the total, 6.55% had hypertension; 13.11% had microhaematuria. After initial treatment with steroids, 68.85% had complete remission (CR) and 13.1% had partial remission (PR). Twelve of 14 (85.71%) steroid-resistant cases had CR or PR after alternative immunosuppression with cyclophosphamide, or mycophenolate mofetil. Of all patients, 44.2% had at least one relapse; 8.19% were frequently relapsing and 26.22% were steroid dependent. After a mean follow-up of 149.9 weeks, 38 (61.29%) patients were in CR and 16 (26.22%) in PR with a mean proteinuria of 1.28 g/day, 3 being treated for relapse. Mean serum creatinine was 89.28 ?mol/L (1.01 mg/dL). Fourteen (22.95%) had acute kidney injury (AKI). All but two recovered completely. Conclusions: This single-centre study with a medium-term follow-up shows that majority of patients respond to steroids or alternative immunosuppressants. AKI is common and may not be completely reversible in some cases. äMinimal-change disease in adolescents and adults: epidemiology and the(epmc).pdf DeepDyve Pubget Overpricing