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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Kidney+J
2013 ; 6
(6
): 635-8
Nephropedia Template TP
Clin Kidney J
2013[Dec]; 6
(6
): 635-8
PMID26069833
show ga
Several types of glomerulonephritis associated with dysproteinemia, such as
AL-amyloidosis, light- and heavy-chain deposition disease, and type 1
cryoglobulinemic glomerulopathy, demonstrate monoclonal immunoglobulin
deposition. Progressive glomerulonephritis with monoclonal IgG deposits (PGNMID)
is also known to feature monoclonal glomerular deposits, but most of these cases
occur without underlying disease. We here report a case of recurrent PGNMID that
developed as diffuse cellular crescentic glomerulonephritis 8 years after an
initial diagnosis of membranoproliferative glomerulonephritis (MPGN).
Determination of the monoclonality of the deposited immunoglobulin is vital to
make the correct diagnosis and enable an early administration of aggressive
immunosuppressive therapy.