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10.1074/jbc.M115.648220 http://scihub22266oqcxt.onion/10.1074/jbc.M115.648220 C4432284!4432284!25837251     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2015 ; 290 (20): 12650-63 Nephropedia Template TP {{tp|p=25837251|t=2015. ?Velcro? Engineering of High Affinity CD47 Ectodomain as Signal Regulatory Protein ? (SIRP?) Antagonists That Enhance Antibody-dependent Cellular Phagocytosis* |pdf=|usr=}}{{25837251}} gab.com Text Velcro Engineering of High Affinity CD47 Ectodomain as Signal Regulatory Protein (SIRP ) Antagonists That Enhance Antibody-dependent Cellular Phagocytosis* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25837251 #FOAvip Background: CD47-SIRP? immunoregulatory pathway is an attractive clinical target.Results: ?Velcro? engineering enabled the creation of high affinity CD47 ectodomain that exquisitely targets myeloid cells to potentiate antibody-dependent cellular phagocytosis.Conclusion: ?Velcro? engineering is a powerful tool to enhance protein-protein interactions; Velcro-CD47 could be an adjuvant for cancer immunotherapy.Significance: This study demonstrates a new general affinity maturation approach, which led to an appealing preclinical immunotherapeutic lead. Twit Text FOAVip Velcro Engineering of High Affinity CD47 Ectodomain as Signal Regulatory Protein (SIRP ) Antagonists That Enhance Antibody-dependent Cellular Phagocytosis* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25837251 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25837251 #FOAvip English Wikipedia <ref>{{Cite pmid|25837251}}</ref> ?Velcro? Engineering of High Affinity CD47 Ectodomain as Signal Regulatory Protein ? (SIRP?) Antagonists That Enhance Antibody-dependent Cellular Phagocytosis* #MMPMID25837251 Ho CCM; Guo N; Sockolosky JT; Ring AM; Weiskopf K; Özkan E; Mori Y; Weissman IL; Garcia KC J Biol Chem 2015[May]; 290 (20): 12650-63 PMID25837251show ga Background: CD47-SIRP? immunoregulatory pathway is an attractive clinical target.Results: ?Velcro? engineering enabled the creation of high affinity CD47 ectodomain that exquisitely targets myeloid cells to potentiate antibody-dependent cellular phagocytosis.Conclusion: ?Velcro? engineering is a powerful tool to enhance protein-protein interactions; Velcro-CD47 could be an adjuvant for cancer immunotherapy.Significance: This study demonstrates a new general affinity maturation approach, which led to an appealing preclinical immunotherapeutic lead. ä?Velcro? Engineering of High Affinity CD47 Ectodomain as Signal Regula(epmc).pdf DeepDyve Pubget Overpricing