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10.12688/f1000research.6312.2 http://scihub22266oqcxt.onion/10.12688/f1000research.6312.2 C4431380!4431380 !26069729     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26069729 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       F1000Res 2015 ; 4 (?): 80 Nephropedia Template TP {{tp|p=26069729 |t=2015. Funding source and primary outcome changes in clinical trials registered on ClinicalTrials gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study |pdf=|usr=}}{{26069729 }} gab.com Text Funding source and primary outcome changes in clinical trials registered on ClinicalTrials gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=26069729 #FOAvip BACKGROUND: We and others have shown a significant proportion of interventional trials registered on ClinicalTrials.gov have their primary outcomes altered after the listed study start and completion dates. The objectives of this study were to investigate whether changes made to primary outcomes are associated with the likelihood of reporting a statistically significant primary outcome on ClinicalTrials.gov. METHODS: A cross-sectional analysis of all interventional clinical trials registered on ClinicalTrials.gov as of 20 November 2014 was performed. The main outcome was any change made to the initially listed primary outcome and the time of the change in relation to the trial start and end date. FINDINGS: 13,238 completed interventional trials were registered with ClinicalTrials.gov that also had study results posted on the website. 2555 (19.3%) had one or more statistically significant primary outcomes. Statistical analysis showed that registration year, funding source and primary outcome change after trial completion were associated with reporting a statistically significant primary outcome . CONCLUSIONS:  Funding source and primary outcome change after trial completion are associated with a statistically significant primary outcome report on clinicaltrials.gov. Twit Text FOAVip Funding source and primary outcome changes in clinical trials registered on ClinicalTrials gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=26069729 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26069729 #FOAvip English Wikipedia <ref>{{Cite pmid|26069729 }}</ref> Funding source and primary outcome changes in clinical trials registered on ClinicalTrials gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study #MMPMID26069729 Ramagopalan SV ; Skingsley AP ; Handunnetthi L ; Magnus D ; Klingel M ; Pakpoor J ; Goldacre B F1000Res 2015[]; 4 (?): 80 PMID26069729 show ga BACKGROUND: We and others have shown a significant proportion of interventional trials registered on ClinicalTrials.gov have their primary outcomes altered after the listed study start and completion dates. The objectives of this study were to investigate whether changes made to primary outcomes are associated with the likelihood of reporting a statistically significant primary outcome on ClinicalTrials.gov. METHODS: A cross-sectional analysis of all interventional clinical trials registered on ClinicalTrials.gov as of 20 November 2014 was performed. The main outcome was any change made to the initially listed primary outcome and the time of the change in relation to the trial start and end date. FINDINGS: 13,238 completed interventional trials were registered with ClinicalTrials.gov that also had study results posted on the website. 2555 (19.3%) had one or more statistically significant primary outcomes. Statistical analysis showed that registration year, funding source and primary outcome change after trial completion were associated with reporting a statistically significant primary outcome . CONCLUSIONS:  Funding source and primary outcome change after trial completion are associated with a statistically significant primary outcome report on clinicaltrials.gov. ?Funding source and primary outcome changes in clinical trials register(epmc).pdf DeepDyve Pubget Overpricing