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Imaging Tumor Metabolism using in vivo MR Spectroscopy #MMPMID25815853
Li Y; Park I; Nelson SJ
Cancer J 2015[Mar]; 21 (2): 123-8 PMID25815853show ga
Magnetic resonance spectroscopy (MRS) is a powerful tool for noninvasively investigating normal and abnormal metabolism. When used in combination with imaging strategies, multi-nuclear MRS methods provide detailed biochemical information that can be directly correlated with anatomical features. Hyperpolarized 13C MRS is a new technology that reflects real-time metabolic conversion and is likely to be extremely valuable in managing patients with cancer. This article reviews the use of in vivo31P, 1H, and 13C MRS for assessing cancer metabolism in order to provide information for diagnosis, planning treatment, assessing response to therapy, and predicting survival for patients with cancer.