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2015 ; 29
(5
): 593-601
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Myopic foveoschisis: a clinical review
#MMPMID25744445
Gohil R
; Sivaprasad S
; Han LT
; Mathew R
; Kiousis G
; Yang Y
Eye (Lond)
2015[May]; 29
(5
): 593-601
PMID25744445
show ga
To review the literature on epidemiology, clinical features, diagnostic imaging,
natural history, management, therapeutic approaches, and prognosis of myopic
foveoschisis. A systematic Pubmed search was conducted using search terms:
myopia, myopic, staphyloma, foveoschisis, and myopic foveoschisis. The evidence
base for each section was organised and reviewed. Where possible an authors'
interpretation or conclusion is provided for each section. The term myopic
foveoschisis was first coined in 1999. It is associated with posterior staphyloma
in high myopia, and is often asymptomatic initially but progresses slowly,
leading to loss of central vision from foveal detachment or macular hole
formation. Optical coherence tomography is used to diagnose the splitting of the
neural retina into a thicker inner layer and a thinner outer layer, but compound
variants of the splits have been identified. Vitrectomy with an internal limiting
membrane peel and gas tamponade is the preferred approach for eyes with vision
decline. There has been a surge of new information on myopic foveoschisis.
Advances in optical coherence tomography will continually improve our
understanding of the pathogenesis of retinal splitting, and the mechanisms that
lead to macular damage and visual loss. Currently, there is a good level of
consensus that surgical intervention should be considered when there is
progressive visual decline from myopic foveoschisis.
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