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10.1155/2015/425708 http://scihub22266oqcxt.onion/10.1155/2015/425708 C4429193!4429193!26064420     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oxid+Med+Cell+Longev 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=26064420|t=2015. Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells |pdf=|usr=}}{{26064420}} gab.com Text Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells JO: Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=26064420 #FOAvip Increasing evidence indicates that most of the tumors are sustained by a distinct population of cancer stem cells (CSCs), which are responsible for growth, metastasis, invasion, and recurrence. CSCs are typically characterized by self-renewal, the key biological process allowing continuous tumor proliferation, as well as by differentiation potential, which leads to the formation of the bulk of the tumor mass. CSCs have several advantages over the differentiated cancer cell populations, including the resistance to radio- and chemotherapy, and their gene-expression programs have been shown to correlate with poor clinical outcome, further supporting the relevance of stemness properties in cancer. The observation that CSCs possess enhanced mechanisms of protection from reactive oxygen species (ROS) induced stress and a different metabolism from the differentiated part of the tumor has paved the way to develop drugs targeting CSC specific signaling. In this review, we describe the role of ROS and of ROS-related microRNAs in the establishment and maintenance of self-renewal and differentiation capacities of CSCs. Twit Text FOAVip Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells ????Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=26064420 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26064420 #FOAvip English Wikipedia <ref>{{Cite pmid|26064420}}</ref> Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells #MMPMID26064420 Dando I; Cordani M; Dalla Pozza E; Biondani G; Donadelli M; Palmieri M Oxid Med Cell Longev 2015[]; 2015 (ä): ä PMID26064420show ga Increasing evidence indicates that most of the tumors are sustained by a distinct population of cancer stem cells (CSCs), which are responsible for growth, metastasis, invasion, and recurrence. CSCs are typically characterized by self-renewal, the key biological process allowing continuous tumor proliferation, as well as by differentiation potential, which leads to the formation of the bulk of the tumor mass. CSCs have several advantages over the differentiated cancer cell populations, including the resistance to radio- and chemotherapy, and their gene-expression programs have been shown to correlate with poor clinical outcome, further supporting the relevance of stemness properties in cancer. The observation that CSCs possess enhanced mechanisms of protection from reactive oxygen species (ROS) induced stress and a different metabolism from the differentiated part of the tumor has paved the way to develop drugs targeting CSC specific signaling. In this review, we describe the role of ROS and of ROS-related microRNAs in the establishment and maintenance of self-renewal and differentiation capacities of CSCs. äAntioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells (epmc).pdf DeepDyve Pubget Overpricing