Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25972172
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Neurosci
2015 ; 35
(19
): 7443-59
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Neurons in the Primate Medial Basal Forebrain Signal Combined Information about
Reward Uncertainty, Value, and Punishment Anticipation
#MMPMID25972172
Monosov IE
; Leopold DA
; Hikosaka O
J Neurosci
2015[May]; 35
(19
): 7443-59
PMID25972172
show ga
It has been suggested that the basal forebrain (BF) exerts strong influences on
the formation of memory and behavior. However, what information is used for the
memory-behavior formation is unclear. We found that a population of neurons in
the medial BF (medial septum and diagonal band of Broca) of macaque monkeys
encodes a unique combination of information: reward uncertainty, expected reward
value, anticipation of punishment, and unexpected reward and punishment. The
results were obtained while the monkeys were expecting (often with uncertainty) a
rewarding or punishing outcome during a Pavlovian procedure, or unexpectedly
received an outcome outside the procedure. In vivo anterograde tracing using
manganese-enhanced MRI suggested that the major recipient of these signals is the
intermediate hippocampal formation. Based on these findings, we hypothesize that
the medial BF identifies various contexts and outcomes that are critical for
memory processing in the hippocampal formation.