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10.1016/j.schres.2014.10.019

http://scihub22266oqcxt.onion/10.1016/j.schres.2014.10.019
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suck abstract from ncbi


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pmid25458567
      Schizophr+Res 2015 ; 167 (1-3 ): 91-7
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  • Searching human brain for mechanisms of psychiatric disorders Implications for studies on schizophrenia #MMPMID25458567
  • Berretta S ; Heckers S ; Benes FM
  • Schizophr Res 2015[Sep]; 167 (1-3 ): 91-7 PMID25458567 show ga
  • In the past 25years, research on the human brain has been providing a clear path toward understanding the pathophysiology of psychiatric illnesses. The successes that have been accrued are matched by significant difficulties identifying and controlling a large number of potential confounding variables. By systematically and effectively accounting for unwanted variance in data from imaging and postmortem human brain studies, meaningful and reliable information regarding the pathophysiology of human brain disorders can be obtained. This perspective paper focuses on postmortem investigations to discuss some of the most challenging sources of variance, including diagnosis, comorbidity, substance abuse and pharmacological treatment, which confound investigations of the human brain.
  • |*Diagnosis [MESH]
  • |Brain/*pathology [MESH]
  • |Comorbidity [MESH]
  • |Humans [MESH]


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