Natural Evolution of Broadly Neutralizing Antibodies #MMPMID25910199
Alter G; Barouch DH
Cell 2015[Apr]; 161 (3): 427-8 PMID25910199show ga
Wu et al. couple next generation sequencing with structural analysis to illuminate the key processes that enable the natural evolution and selection of broadly neutralizing antibodies to HIV-1, providing a potential roadmap for the development of HIV-1 vaccine strategies to accelerate the induction of protective antibodies.