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10.1038/nrneph.2014.197

http://scihub22266oqcxt.onion/10.1038/nrneph.2014.197
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C4425203!4425203!25347945
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suck abstract from ncbi

pmid25347945      Nat+Rev+Nephrol 2014 ; 10 (12): 678-80
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  • Molecular phenotyping of T cell-mediated rejection #MMPMID25347945
  • Chong AS; Perkins DL
  • Nat Rev Nephrol 2014[Dec]; 10 (12): 678-80 PMID25347945show ga
  • A new study has reported a molecular signature of T cell-mediated rejection in human kidney transplant biopsy samples that is enriched for effector T cells, interferon-? and macrophages. Inhibitors of T cell activation, such as CTLA4 and PDL1, were also prominent, raising the possibility that these immunological constrains could be harnessed by therapies for treating rejection.
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