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Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Endosc+Int+Open 2014 ; 2 (4): E201-6 Nephropedia Template TP
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Impact of balloon-assisted enteroscopy on the diagnosis and management of suspected and established small-bowel Crohn?s disease #MMPMID26135093
Navaneethan U; Vargo JJ; Menon KVN; Sanaka MR; Tsai CJ
Endosc Int Open 2014[Dec]; 2 (4): E201-6 PMID26135093show ga
Background and aims: The role of recently developed balloon-assisted enteroscopy (BAE) in small-bowel Crohn?s disease (CD) is not well established. The purpose of this study is to determine the clinical impact of BAE on patients with suspected and established small-bowel CD.Methods: This study included 22 patients (group A) with suspected small-bowel CD and 43 patients (group B) with established small-bowel CD with or without previous surgery, who underwent BAE, in a prospective BAE registry of a US academic medical institution. All underwent abdominal imaging studies including computed tomography (CT) or magnetic resonance (MR) enterography before BAE. The main outcome measurements were diagnostic yield and clinical outcomes.Results: In total, 78 BAE procedures were carried out in 65 patients. In group A (n?=?22, 25 BAE procedures), enteroscopy led to a diagnosis of CD in six patients (27.3?%). Non-steroidal anti-inflammatory drug-related enteropathy was diagnosed in three patients (13.6?%), whereas no lesions were found in the remaining 13 patients. In group B (n?=?43, 53 BAE procedures) enteroscopy revealed active intestinal inflammation with ulcers and/or luminal stenosis in 18 patients (41.9?%), which led to a change and escalation of medical therapy. Five patients without active ulcers underwent successful dilation of small-bowel strictures with resulting resolution of obstructive symptoms. Of the 78 BAE procedures, two patients (2.6?%) had bleeding complications which were successfully treated conservatively. One patient (1.3?%) underwent surgery due to procedure-related perforation.Conclusions: The use of BAE may help improve management in patients with suspected and established small-bowel CD.
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Endosc+Int+Open 2014 ; 2 (4): E201-6
