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2014 ; 2
(4
): E201-6
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Impact of balloon-assisted enteroscopy on the diagnosis and management of
suspected and established small-bowel Crohn s disease
#MMPMID26135093
Navaneethan U
; Vargo JJ
; Menon KV
; Sanaka MR
; Tsai CJ
Endosc Int Open
2014[Dec]; 2
(4
): E201-6
PMID26135093
show ga
BACKGROUND AND AIMS: The role of recently developed balloon-assisted enteroscopy
(BAE) in small-bowel Crohn's disease (CD) is not well established. The purpose of
this study is to determine the clinical impact of BAE on patients with suspected
and established small-bowel CD. METHODS: This study included 22 patients (group
A) with suspected small-bowel CD and 43 patients (group B) with established
small-bowel CD with or without previous surgery, who underwent BAE, in a
prospective BAE registry of a US academic medical institution. All underwent
abdominal imaging studies including computed tomography (CT) or magnetic
resonance (MR) enterography before BAE. The main outcome measurements were
diagnostic yield and clinical outcomes. RESULTS: In total, 78 BAE procedures were
carried out in 65 patients. In group A (n?=?22, 25 BAE procedures), enteroscopy
led to a diagnosis of CD in six patients (27.3?%). Non-steroidal
anti-inflammatory drug-related enteropathy was diagnosed in three patients
(13.6?%), whereas no lesions were found in the remaining 13 patients. In group B
(n?=?43, 53 BAE procedures) enteroscopy revealed active intestinal inflammation
with ulcers and/or luminal stenosis in 18 patients (41.9?%), which led to a
change and escalation of medical therapy. Five patients without active ulcers
underwent successful dilation of small-bowel strictures with resulting resolution
of obstructive symptoms. Of the 78 BAE procedures, two patients (2.6?%) had
bleeding complications which were successfully treated conservatively. One
patient (1.3?%) underwent surgery due to procedure-related perforation.
CONCLUSIONS: The use of BAE may help improve management in patients with
suspected and established small-bowel CD.