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10.1136/bcr-2014-209057

http://scihub22266oqcxt.onion/10.1136/bcr-2014-209057
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C4422923!4422923!25926585
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suck abstract from ncbi


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pmid25926585      BMJ+Case+Rep 2015 ; 2015 (ä): ä
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  • Emergency reversal of dabigatran for emergency surgery #MMPMID25926585
  • Puttick T; Bahl R; Mohamedbhai H
  • BMJ Case Rep 2015[]; 2015 (ä): ä PMID25926585show ga
  • An 80-year-old woman had the anticoagulant effect of dabigatran etexilate reversed using factor eight inhibitor bypassing activity (FEIBA) in order to facilitate emergency surgery for an incarcerated femoral hernia. She had atrial fibrillation was taking the anticoagulant for stroke prevention. That afternoon her international normalised ratio (INR) was 1.3 and activated partial thromboplastin time ratio (APPTr) was 2.17, having taken dabigatran that morning. 3000?units of FEIBA and 10?mg of vitamin K were administered and she was taken to theatre for emergency surgery. Surgery was successful, total blood loss was less than 100?mL and there were no complications. The following morning she had an INR of 1.1 and APPTr of 1.49. She made an uneventful postoperative recovery and was discharged home. There is a limited evidence base guiding practice in the clinical scenario described. The only controlled studies available are animal experiments.
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