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10.1152/ajpcell.00321.2013

http://scihub22266oqcxt.onion/10.1152/ajpcell.00321.2013
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C4422352!4422352 !24740535
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suck abstract from ncbi


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pmid24740535
      Am+J+Physiol+Cell+Physiol 2014 ; 306 (11 ): C987-96
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  • Cellular mechanisms of tissue fibrosis 7 New insights into the cellular mechanisms of pulmonary fibrosis #MMPMID24740535
  • Barkauskas CE ; Noble PW
  • Am J Physiol Cell Physiol 2014[Jun]; 306 (11 ): C987-96 PMID24740535 show ga
  • Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by severe and progressive scar formation in the gas-exchange regions of the lung. Despite years of research, therapeutic treatments remain elusive and there is a pressing need for deeper mechanistic insights into the pathogenesis of the disease. In this article, we review our current knowledge of the triggers and/or perpetuators of pulmonary fibrosis with special emphasis on the alveolar epithelium and the underlying mesenchyme. In doing so, we raise a number of questions highlighting critical voids and limitations in our current understanding and study of this disease.
  • |Animals [MESH]
  • |Fibroblasts/metabolism/*pathology [MESH]
  • |Humans [MESH]
  • |Pulmonary Alveoli/pathology [MESH]
  • |Pulmonary Fibrosis/metabolism/*pathology [MESH]


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