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2015 ; 473
(6
): 1988-99
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Incidence of Low Back Pain After Lumbar Discectomy for Herniated Disc and Its
Effect on Patient-reported Outcomes
#MMPMID25694267
Parker SL
; Mendenhall SK
; Godil SS
; Sivasubramanian P
; Cahill K
; Ziewacz J
; McGirt MJ
Clin Orthop Relat Res
2015[Jun]; 473
(6
): 1988-99
PMID25694267
show ga
BACKGROUND: Long-term postdiscectomy degenerative disc disease and low back pain
is a well-recognized disorder; however, its patient-centered characterization and
quantification are lacking. QUESTIONS/PURPOSES: We performed a systematic
literature review and prospective longitudinal study to determine the frequency
of recurrent back pain after discectomy and quantify its effect on
patient-reported outcomes (PROs). METHODS: A MEDLINE search was performed to
identify studies reporting on the frequency of recurrent back pain, same-level
recurrent disc herniation, and reoperation after primary lumbar discectomy. After
excluding studies that did not report the percentage of patients with persistent
back or leg pain more than 6 months after discectomy or did not report the rate
of same level recurrent herniation, 90 studies, which in aggregate had evaluated
21,180 patients, were included in the systematic review portion of this study.
For the longitudinal study, all patients undergoing primary lumbar discectomy
between October 2010 and March 2013 were enrolled into our prospective spine
registry. One hundred fifteen patients were more than 12 months out from surgery,
103 (90%) of whom were available for 1-year outcomes assessment. PROs were
prospectively assessed at baseline, 3 months, 1 year, and 2 years. The threshold
of deterioration used to classify recurrent back pain was the minimum clinically
important difference in back pain (Numeric Rating Scale Back Pain [NRS-BP]) or
Disability (Oswestry Disability Index [ODI]), which were 2.5 of 10 points and 20
of 100 points, respectively. RESULTS SYSTEMATIC REVIEW: The proportion of
patients reporting short-term (6-24 months) and long-term (> 24 months) recurrent
back pain ranged from 3% to 34% and 5% to 36%, respectively. The 2-year incidence
of recurrent disc herniation ranged from 0% to 23% and the frequency of
reoperation ranged from 0% to 13%. PROSPECTIVE STUDY: At 1-year and 2-year
followup, 22% and 26% patients reported worsening of low back pain (NRS:
5.3 ± 2.5 versus 2.7 ± 2.8, p < 0.001) or disability (ODI%: 32 ± 18 versus
21 ± 18, p < 0.001) compared with 3 months. CONCLUSIONS: In a systematic
literature review and prospective outcomes study, the frequency of same-level
disc herniation requiring reoperation was 6%. Two-year recurrent low back pain
may occur in 15% to 25% of patients depending on the level of recurrent pain
considered clinically important, and this leads to worse PROs at 1 and 2 years
postoperatively.