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2015 ; 34
(5
): 1063-76
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Graph-Based Airway Tree Reconstruction From Chest CT Scans: Evaluation of
Different Features on Five Cohorts
#MMPMID25438305
Bauer C
; Eberlein M
; Beichel RR
IEEE Trans Med Imaging
2015[May]; 34
(5
): 1063-76
PMID25438305
show ga
We present a graph-based framework for airway tree reconstruction from
computerized tomography (CT) scans and evaluate the performance of different
feature categories and their combinations on five lung cohorts. The approach
consists of two main processing steps. First, potential airway branch and
connection candidates are identified and represented by a graph structure with
weighted nodes and edges, respectively. Second, an optimization algorithm is
utilized for generating an airway detection result by selecting a subset of
airway branches and connections based on graph weights derived from image
features. The performance of the algorithm with different feature categories and
their combinations was assessed on a set of 50 lung CT scans from five different
cohorts, including normal and diseased lungs. Results show trade-offs between
feature categories/combinations in terms of correctly (true positive) and
incorrectly (false positive) identified airways. Also, the performance of
features in dependence of lung cohort was analyzed. Across all cohorts, a good
trade-off with high true positive rate (TPR) and low false positive rate (FPR)
was achieved by a combination of gray-value, local shape, and structural
features. This combination enabled extracting 91.80% of reference airways (TPR)
in combination with a low FPR of 1.00%. In addition, this variant was evaluated
on the public EXACT'09 test set, and a comparison with other airway detection
approaches is provided. One of the main advantages of the presented method is
that it is robust against local disturbances/artifacts or other ambiguities that
are frequently occurring in lung CT scans.