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10.1074/jbc.M115.645788

http://scihub22266oqcxt.onion/10.1074/jbc.M115.645788
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suck abstract from ncbi


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pmid25759389      J+Biol+Chem 2015 ; 290 (18): 11403-16
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  • Vasodilator-stimulated Phosphoprotein (VASP) Regulates Actin Polymerization and Contraction in Airway Smooth Muscle by a Vinculin-dependent Mechanism* #MMPMID25759389
  • Wu Y; Gunst SJ
  • J Biol Chem 2015[May]; 290 (18): 11403-16 PMID25759389show ga
  • Background: The function of vasodilator-stimulated phosphoprotein (VASP) in regulating actin polymerization during airway smooth muscle contraction is unknown.Results: VASP activity requires phosphorylation at Ser157, recruitment to the membrane, and interaction with activated vinculin.Conclusion: VASP regulates actin polymerization and contraction in smooth muscle by a unique mechanism.Significance: The mechanism of VASP function is important for understanding actin dynamics in cells.
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