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10.1074/jbc.M115.643189

http://scihub22266oqcxt.onion/10.1074/jbc.M115.643189
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C4416840!4416840!25773539
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suck abstract from ncbi


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pmid25773539      J+Biol+Chem 2015 ; 290 (18): 11349-64
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  • The Chromatin Regulator Brpf1 Regulates Embryo Development and Cell Proliferation* #MMPMID25773539
  • You L; Yan K; Zou J; Zhao H; Bertos NR; Park M; Wang E; Yang XJ
  • J Biol Chem 2015[May]; 290 (18): 11349-64 PMID25773539show ga
  • Background: Deletion of the mouse Brpf1 gene causes embryonic lethality, but the resulting defects await characterization.Results: The vasculature, neural tube, and cell proliferation are abnormal in the mutant.Conclusion: Brpf1 is important for embryo development and cell cycle control.Significance: This study identifies a critical role of a multivalent chromatin regulator in embryogenesis and cell proliferation.
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