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10.4155/cli.14.126

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suck abstract from ncbi


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pmid25932321
      Clin+Investig+(Lond) 2015 ; 5 (2 ): 145-159
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  • Person-centric clinical trials: defining the N-of-1 clinical trial utilizing a practice-based translational network #MMPMID25932321
  • Curro FA ; Robbins DA ; Naftolin F ; Grill AC ; Vena D ; Terracio L
  • Clin Investig (Lond) 2015[]; 5 (2 ): 145-159 PMID25932321 show ga
  • A person-centric clinical trial is inclusive of both the investigator and the person and as such represents point-of-use data generated at the practice level and encompasses both health and disease. Raising the clinical encounter to a research encounter and providing an infrastructure to support a level of quality assurance creates a synergy for efficiency for healthcare delivery. The interface of translational studies and clinical research poses an opportunity, whereby person-centricity can support transparency, facilitate informed consent, improve safety, enhance recruitment and compliance, improve dissemination of results, implement change and help close the translational gap. The model represents robust clinical data from persons of record allowing for improved interpretation of drug/device side-effects and for regulatory reviewers to expedite the approval process.
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