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10.1089/ten.tec.2014.0258 http://scihub22266oqcxt.onion/10.1089/ten.tec.2014.0258 C4410304!4410304!25390971     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Tissue+Eng+Part+C+Methods 2015 ; 21 (5): 509-17 Nephropedia Template TP {{tp|p=25390971|t=2015. Patterning Vascular Networks In Vivo for Tissue Engineering Applications |pdf=|usr=}}{{25390971}} gab.com Text Patterning Vascular Networks In Vivo for Tissue Engineering Applications JO: Tissue Eng Part C Methods http://www.kidney.de/pget.php?&tw=1&pmid=25390971 #FOAvip The ultimate design of functionally therapeutic engineered tissues and organs will rely on our ability to engineer vasculature that can meet tissue-specific metabolic needs. We recently introduced an approach for patterning the formation of functional spatially organized vascular architectures within engineered tissues in vivo. Here, we now explore the design parameters of this approach and how they impact the vascularization of an engineered tissue construct after implantation. We used micropatterning techniques to organize endothelial cells (ECs) into geometrically defined ?cords,? which in turn acted as a template after implantation for the guided formation of patterned capillaries integrated with the host tissue. We demonstrated that the diameter of the cords before implantation impacts the location and density of the resultant capillary network. Inclusion of mural cells to the vascularization response appears primarily to impact the dynamics of vascularization. We established that clinically relevant endothelial sources such as induced pluripotent stem cell-derived ECs and human microvascular endothelial cells can drive vascularization within this system. Finally, we demonstrated the ability to control the juxtaposition of parenchyma with perfused vasculature by implanting cords containing a mixture of both a parenchymal cell type (hepatocytes) and ECs. These findings define important characteristics that will ultimately impact the design of vasculature structures that meet tissue-specific needs. Twit Text FOAVip Patterning Vascular Networks In Vivo for Tissue Engineering Applications ????Tissue Eng Part C Methods http://www.kidney.de/pget.php?&tw=1&pmid=25390971 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25390971 #FOAvip English Wikipedia <ref>{{Cite pmid|25390971}}</ref> Patterning Vascular Networks In Vivo for Tissue Engineering Applications #MMPMID25390971 Chaturvedi RR; Stevens KR; Solorzano RD; Schwartz RE; Eyckmans J; Baranski JD; Stapleton SC; Bhatia SN; Chen CS Tissue Eng Part C Methods 2015[May]; 21 (5): 509-17 PMID25390971show ga The ultimate design of functionally therapeutic engineered tissues and organs will rely on our ability to engineer vasculature that can meet tissue-specific metabolic needs. We recently introduced an approach for patterning the formation of functional spatially organized vascular architectures within engineered tissues in vivo. Here, we now explore the design parameters of this approach and how they impact the vascularization of an engineered tissue construct after implantation. We used micropatterning techniques to organize endothelial cells (ECs) into geometrically defined ?cords,? which in turn acted as a template after implantation for the guided formation of patterned capillaries integrated with the host tissue. We demonstrated that the diameter of the cords before implantation impacts the location and density of the resultant capillary network. Inclusion of mural cells to the vascularization response appears primarily to impact the dynamics of vascularization. We established that clinically relevant endothelial sources such as induced pluripotent stem cell-derived ECs and human microvascular endothelial cells can drive vascularization within this system. Finally, we demonstrated the ability to control the juxtaposition of parenchyma with perfused vasculature by implanting cords containing a mixture of both a parenchymal cell type (hepatocytes) and ECs. These findings define important characteristics that will ultimately impact the design of vasculature structures that meet tissue-specific needs. äPatterning Vascular Networks In Vivo for Tissue Engineering Applicatio(epmc).pdf DeepDyve Pubget Overpricing