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10.3727/105221615X14181438356210 http://scihub22266oqcxt.onion/10.3727/105221615X14181438356210 C4410163!4410163 !25700367     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25700367 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Gene+Expr 2015 ; 16 (3 ): 109-27 Nephropedia Template TP {{tp|p=25700367 |t=2015. PDGFR? in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer |pdf=|usr=}}{{25700367 }} gab.com Text PDGFR in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer JO: Gene Expr http://www.kidney.de/pget.php?&tw=1&pmid=25700367 #FOAvip Platelet-derived growth factor receptor ? (PDGFR?) is an isoform of the PDGFR family of tyrosine kinase receptors involved in cell proliferation, survival, differentiation, and growth. In this review, we highlight the role of PDGFR? and the current evidence of its expression and activities in liver development, regeneration, and pathology-including fibrosis, cirrhosis, and liver cancer. Studies elucidating PDGFR? signaling in processes ranging from profibrotic signaling, angiogenesis, and oxidative stress to epithelial-to-mesenchymal transition point toward PDGFR? as a potential therapeutic target in various hepatic pathologies, including hepatic fibrosis and liver cancer. Furthermore, PDGFR? localization and modulation during liver development and regeneration may lend insight into its potential roles in various pathologic states. We will also briefly discuss some of the current targeted treatments for PDGFR?, including multi receptor tyrosine kinase inhibitors and PDGFR?-specific inhibitors. Twit Text FOAVip PDGFR in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer ????Gene Expr http://www.kidney.de/pget.php?&tw=1&pmid=25700367 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25700367 #FOAvip English Wikipedia <ref>{{Cite pmid|25700367 }}</ref> PDGFR? in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer #MMPMID25700367 Kikuchi A ; Monga SP Gene Expr 2015[]; 16 (3 ): 109-27 PMID25700367 show ga Platelet-derived growth factor receptor ? (PDGFR?) is an isoform of the PDGFR family of tyrosine kinase receptors involved in cell proliferation, survival, differentiation, and growth. In this review, we highlight the role of PDGFR? and the current evidence of its expression and activities in liver development, regeneration, and pathology-including fibrosis, cirrhosis, and liver cancer. Studies elucidating PDGFR? signaling in processes ranging from profibrotic signaling, angiogenesis, and oxidative stress to epithelial-to-mesenchymal transition point toward PDGFR? as a potential therapeutic target in various hepatic pathologies, including hepatic fibrosis and liver cancer. Furthermore, PDGFR? localization and modulation during liver development and regeneration may lend insight into its potential roles in various pathologic states. We will also briefly discuss some of the current targeted treatments for PDGFR?, including multi receptor tyrosine kinase inhibitors and PDGFR?-specific inhibitors. |Cell Differentiation/genetics [MESH] |Cell Proliferation/genetics [MESH] |Humans [MESH] |Liver Cirrhosis/*genetics/pathology [MESH] |Liver Neoplasms/*genetics/pathology [MESH] |Liver Regeneration/genetics [MESH] |Liver/*metabolism/physiopathology [MESH] |Molecular Targeted Therapy [MESH] |Receptor, Platelet-Derived Growth Factor alpha/antagonists & inhibitors/*genetics/metabolism [MESH]PDGFR? in liver pathophysiology: emerging roles in development, regene(epmc).pdf DeepDyve Pubget Overpricing