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10.1016/j.hrthm.2015.01.011 http://scihub22266oqcxt.onion/10.1016/j.hrthm.2015.01.011 C4410060!4410060!25625719     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Heart+Rhythm 2015 ; 12 (5): 1062-70 Nephropedia Template TP {{tp|p=25625719|t=2015. Next Generation Sequencing for the Diagnosis of Cardiac Arrhythmia Syndromes |pdf=|usr=}}{{25625719}} gab.com Text Next Generation Sequencing for the Diagnosis of Cardiac Arrhythmia Syndromes JO: Heart Rhythm http://www.kidney.de/pget.php?&tw=1&pmid=25625719 #FOAvip Inherited arrhythmia syndromes are collectively associated with substantial morbidity, yet our understanding of the genetic architecture of these conditions remains limited. Recent technological advances in DNA sequencing have led to the commercialization of genetic testing now widely available in clinical practice. In particular, next generation sequencing allows the large-scale and rapid assessment of entire genomes. Although next generation sequencing represents a major technological advance, it has introduced numerous challenges with respect to the interpretation of genetic variation, and has opened a veritable floodgate of biological data of unknown clinical significance to practitioners. In this review, we discuss current genetic testing indications for inherited arrhythmia syndromes, broadly outline characteristics of next generation sequencing techniques, and highlight challenges associated with such testing. We further summarize future directions that will be necessary to address to enable the widespread adoption of next generation sequencing in the routine management of patients with inherited arrhythmia syndromes. Twit Text FOAVip Next Generation Sequencing for the Diagnosis of Cardiac Arrhythmia Syndromes ????Heart Rhythm http://www.kidney.de/pget.php?&tw=1&pmid=25625719 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25625719 #FOAvip English Wikipedia <ref>{{Cite pmid|25625719}}</ref> Next Generation Sequencing for the Diagnosis of Cardiac Arrhythmia Syndromes #MMPMID25625719 Lubitz SA; Ellinor PT Heart Rhythm 2015[May]; 12 (5): 1062-70 PMID25625719show ga Inherited arrhythmia syndromes are collectively associated with substantial morbidity, yet our understanding of the genetic architecture of these conditions remains limited. Recent technological advances in DNA sequencing have led to the commercialization of genetic testing now widely available in clinical practice. In particular, next generation sequencing allows the large-scale and rapid assessment of entire genomes. Although next generation sequencing represents a major technological advance, it has introduced numerous challenges with respect to the interpretation of genetic variation, and has opened a veritable floodgate of biological data of unknown clinical significance to practitioners. In this review, we discuss current genetic testing indications for inherited arrhythmia syndromes, broadly outline characteristics of next generation sequencing techniques, and highlight challenges associated with such testing. We further summarize future directions that will be necessary to address to enable the widespread adoption of next generation sequencing in the routine management of patients with inherited arrhythmia syndromes. äNext Generation Sequencing for the Diagnosis of Cardiac Arrhythmia Syn(epmc).pdf DeepDyve Pubget Overpricing