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10.1126/science.1258025 http://scihub22266oqcxt.onion/10.1126/science.1258025 C4409937!4409937!25431490     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25431490&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Science 2015 ; 347 (6219): 266-9 Nephropedia Template TP {{tp|p=25431490|t=2015. Commensal microbes and interferon-? determine persistence of enteric murine norovirus infection |pdf=|usr=}}{{25431490}} gab.com Text Commensal microbes and interferon- determine persistence of enteric murine norovirus infection JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=25431490 #FOAvip The capacity of human norovirus (NoV), which causes >90% of global epidemic nonbacterial gastroenteritis, to infect a subset of people persistently may contribute to its spread. How such enteric viruses establish persistent infections is not well understood. We found that antibiotics prevented persistent murine norovirus (MNoV) infection, an effect that was reversed by replenishment of the bacterial microbiota. Antibiotics did not prevent tissue infection or affect systemic viral replication but acted specifically in the intestine. The receptor for the antiviral cytokine interferon-?, Ifnlr1, as well as the transcription factors Stat1 and Irf3, were required for antibiotics to prevent viral persistence. Thus, the bacterial microbiome fosters enteric viral persistence in a manner counteracted by specific components of the innate immune system. Twit Text FOAVip Commensal microbes and interferon- determine persistence of enteric murine norovirus infection ????Science http://www.kidney.de/pget.php?&tw=1&pmid=25431490 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25431490 #FOAvip English Wikipedia <ref>{{Cite pmid|25431490}}</ref> Commensal microbes and interferon-? determine persistence of enteric murine norovirus infection #MMPMID25431490 Baldridge MT; Nice TJ; McCune BT; Yokoyama CC; Kambal A; Wheadon M; Diamond MS; Ivanova Y; Artyomov M; Virgin HW Science 2015[Jan]; 347 (6219): 266-9 PMID25431490show ga The capacity of human norovirus (NoV), which causes >90% of global epidemic nonbacterial gastroenteritis, to infect a subset of people persistently may contribute to its spread. How such enteric viruses establish persistent infections is not well understood. We found that antibiotics prevented persistent murine norovirus (MNoV) infection, an effect that was reversed by replenishment of the bacterial microbiota. Antibiotics did not prevent tissue infection or affect systemic viral replication but acted specifically in the intestine. The receptor for the antiviral cytokine interferon-?, Ifnlr1, as well as the transcription factors Stat1 and Irf3, were required for antibiotics to prevent viral persistence. Thus, the bacterial microbiome fosters enteric viral persistence in a manner counteracted by specific components of the innate immune system. äCommensal microbes and interferon-? determine persistence of enteric m(epmc).pdf DeepDyve Pubget Overpricing