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10.1016/j.tcb.2014.12.009 http://scihub22266oqcxt.onion/10.1016/j.tcb.2014.12.009 C4409512!4409512!25639489     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Cell+Biol 2015 ; 25 (5): 308-15 Nephropedia Template TP {{tp|p=25639489|t=2015. Mechanisms of inflammasome activation: recent advances and novel insights |pdf=|usr=}}{{25639489}} gab.com Text Mechanisms of inflammasome activation: recent advances and novel insights JO: Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=25639489 #FOAvip Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and other danger signals. Typically inflammasome complexes contain a sensor protein, an adaptor protein and a zymogen, procaspase-1. Formation of inflammasome assembly results in processing of inactive procasase-1 into an active cysteine protease enzyme, caspase-1, which subsequently activates proinflammatory cytokines, IL-1? and IL-18, and induces pyroptosis, a highly pyrogenic inflammatory form of cell death. Studies over the last year have unveiled exciting new players and regulatory pathways that are involved in traditional inflammasome signaling, some of them even challenging the existing dogma. This review outlines these new insights in inflammasome research and discusses areas that warrant further exploration. Twit Text FOAVip Mechanisms of inflammasome activation: recent advances and novel insights ????Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=25639489 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25639489 #FOAvip English Wikipedia <ref>{{Cite pmid|25639489}}</ref> Mechanisms of inflammasome activation: recent advances and novel insights #MMPMID25639489 Vanaja S; Rathinam VK; Fitzgerald KA Trends Cell Biol 2015[May]; 25 (5): 308-15 PMID25639489show ga Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and other danger signals. Typically inflammasome complexes contain a sensor protein, an adaptor protein and a zymogen, procaspase-1. Formation of inflammasome assembly results in processing of inactive procasase-1 into an active cysteine protease enzyme, caspase-1, which subsequently activates proinflammatory cytokines, IL-1? and IL-18, and induces pyroptosis, a highly pyrogenic inflammatory form of cell death. Studies over the last year have unveiled exciting new players and regulatory pathways that are involved in traditional inflammasome signaling, some of them even challenging the existing dogma. This review outlines these new insights in inflammasome research and discusses areas that warrant further exploration. äMechanisms of inflammasome activation: recent advances and novel insig(epmc).pdf DeepDyve Pubget Overpricing