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10.1016/j.jstrokecerebrovasdis.2014.12.039 http://scihub22266oqcxt.onion/10.1016/j.jstrokecerebrovasdis.2014.12.039 C4408219!4408219!25817614     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Stroke+Cerebrovasc+Dis 2015 ; 24 (5): 1052-8 Nephropedia Template TP {{tp|p=25817614|t=2015. Vertebrobasilar ectasia in patients with lacunar stroke: The SPS3 trial |pdf=|usr=}}{{25817614}} gab.com Text Vertebrobasilar ectasia in patients with lacunar stroke: The SPS3 trial JO: J Stroke Cerebrovasc Dis http://www.kidney.de/pget.php?&tw=1&pmid=25817614 #FOAvip Objective: The clinical implications of vertebrobasilar ectasia (VBE) in patients with cerebral small artery disease are not well defined. We investigated whether VBE is associated with recurrent stroke, major hemorrhage, and death in a large cohort of patients with recent lacunar stroke. Materials and methods: Maximum diameters of the vertebral and basilar arteries were measured by magnetic resonance angiography and computed tomographic angiography in 2621 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial. VBE was defined a priori as basilar artery >4.5 mm and/or vertebral artery >4.0 mm. Patient characteristics and risks of stroke recurrence and mortality during follow-up (median 3.5 years) were compared between patients with and without VBE. Results: VBE affecting ?1 artery was present in 200 (7.6%) patients. Patient features independently associated with VBE were increasing age, male sex, white race-ethnicity, hypertension, and higher baseline diastolic blood pressure. Baseline systolic blood pressure was inversely associated with VBE. After adjustment for other risk factors, VBE was not predictive of recurrent stroke (HR 1.3, 95% CI 0.85-1.9) or major hemorrhage (HR 1.5, CI 0.94-2.6), but was of death (HR 1.7, CI 1.1-2.7). Conclusion: In this large well-characterized cohort of patients with recent lacunar stroke, VBE was predictive of death, but not recurrent stroke or major hemorrhage. In these exploratory analyses, the frequency of VBE was directly related to diastolic blood pressure but inversely related to systolic blood pressure. Twit Text FOAVip Vertebrobasilar ectasia in patients with lacunar stroke: The SPS3 trial ????J Stroke Cerebrovasc Dis http://www.kidney.de/pget.php?&tw=1&pmid=25817614 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25817614 #FOAvip English Wikipedia <ref>{{Cite pmid|25817614}}</ref> Vertebrobasilar ectasia in patients with lacunar stroke: The SPS3 trial #MMPMID25817614 Nakajima M; Pearce LA; Ohara N; Field TS; Bazan C; Anderson DC; Hart RG; Benavente OR J Stroke Cerebrovasc Dis 2015[May]; 24 (5): 1052-8 PMID25817614show ga Objective: The clinical implications of vertebrobasilar ectasia (VBE) in patients with cerebral small artery disease are not well defined. We investigated whether VBE is associated with recurrent stroke, major hemorrhage, and death in a large cohort of patients with recent lacunar stroke. Materials and methods: Maximum diameters of the vertebral and basilar arteries were measured by magnetic resonance angiography and computed tomographic angiography in 2621 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial. VBE was defined a priori as basilar artery >4.5 mm and/or vertebral artery >4.0 mm. Patient characteristics and risks of stroke recurrence and mortality during follow-up (median 3.5 years) were compared between patients with and without VBE. Results: VBE affecting ?1 artery was present in 200 (7.6%) patients. Patient features independently associated with VBE were increasing age, male sex, white race-ethnicity, hypertension, and higher baseline diastolic blood pressure. Baseline systolic blood pressure was inversely associated with VBE. After adjustment for other risk factors, VBE was not predictive of recurrent stroke (HR 1.3, 95% CI 0.85-1.9) or major hemorrhage (HR 1.5, CI 0.94-2.6), but was of death (HR 1.7, CI 1.1-2.7). Conclusion: In this large well-characterized cohort of patients with recent lacunar stroke, VBE was predictive of death, but not recurrent stroke or major hemorrhage. In these exploratory analyses, the frequency of VBE was directly related to diastolic blood pressure but inversely related to systolic blood pressure. äVertebrobasilar ectasia in patients with lacunar stroke: The SPS3 tria(epmc).pdf DeepDyve Pubget Overpricing