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10.1016/j.cub.2015.02.052

http://scihub22266oqcxt.onion/10.1016/j.cub.2015.02.052
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C4406942!4406942!25898100
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suck abstract from ncbi


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pmid25898100      Curr+Biol 2015 ; 25 (8): R326-7
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  • Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra #MMPMID25898100
  • O?Neill JS; Lee KD; Zhang L; Feeney K; Webster SG; Blades MJ; Kyriacou CP; Hastings MH; Wilcockson DC
  • Curr Biol 2015[Apr]; 25 (8): R326-7 PMID25898100show ga
  • In contrast to the well mapped molecular orchestration of circadian timekeeping in terrestrial organisms, the mechanisms that direct tidal and lunar rhythms in marine species are entirely unknown. Using a combination of biochemical and molecular approaches we have identified a series of metabolic markers of the tidal clock of the intertidal isopod Eurydice pulchra. Specifically, we show that the overoxidation of peroxiredoxin (PRX), a conserved marker of circadian timekeeping in terrestrial eukaryotes [1], follows a circatidal (approximately 12.4 hours) pattern in E. pulchra, in register with the tidal pattern of swimming. In parallel, we show that mitochondrially encoded genes are expressed with a circatidal rhythm. Together, these findings demonstrate that PRX overoxidation rhythms are not intrinsically circadian; rather they appear to resonate with the dominant metabolic cycle of an organism, regardless of its frequency. Moreover, they provide the first molecular leads for dissecting the tidal clockwork.
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