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10.1038/ncomms7756 http://scihub22266oqcxt.onion/10.1038/ncomms7756 C4403372!4403372!25854147     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun ä ; 6 (ä): ä Nephropedia Template TP {{tp|p=25854147|t=ä. Processing of visually evoked innate fear by a non-canonical thalamic pathway |pdf=|usr=}}{{25854147}} gab.com Text Processing of visually evoked innate fear by a non-canonical thalamic pathway JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=25854147 #FOAvip The ability of animals to respond to life-threatening stimuli is essential for survival. Although vision provides one of the major sensory inputs for detecting threats across animal species, the circuitry underlying defensive responses to visual stimuli remains poorly defined. Here, we investigate the circuitry underlying innate defensive behaviours elicited by predator-like visual stimuli in mice. Our results demonstrate that neurons in the superior colliculus (SC) are essential for a variety of acute and persistent defensive responses to overhead looming stimuli. Optogenetic mapping revealed that SC projections to the lateral posterior nucleus (LP) of the thalamus, a non-canonical polymodal sensory relay, are sufficient to mimic visually evoked fear responses. In vivo electrophysiology experiments identified a di-synaptic circuit from SC through LP to the lateral amygdale (Amg), and lesions of the Amg blocked the full range of visually evoked defensive responses. Our results reveal a novel collicular?thalamic?Amg circuit important for innate defensive responses to visual threats. Twit Text FOAVip Processing of visually evoked innate fear by a non-canonical thalamic pathway ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=25854147 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25854147 #FOAvip English Wikipedia <ref>{{Cite pmid|25854147}}</ref> Processing of visually evoked innate fear by a non-canonical thalamic pathway #MMPMID25854147 Wei P; Liu N; Zhang Z; Liu X; Tang Y; He X; Wu B; Zhou Z; Liu Y; Li J; Zhang Y; Zhou X; Xu L; Chen L; Bi G; Hu X; Xu F; Wang L Nat Commun ä[]; 6 (ä): ä PMID25854147show ga The ability of animals to respond to life-threatening stimuli is essential for survival. Although vision provides one of the major sensory inputs for detecting threats across animal species, the circuitry underlying defensive responses to visual stimuli remains poorly defined. Here, we investigate the circuitry underlying innate defensive behaviours elicited by predator-like visual stimuli in mice. Our results demonstrate that neurons in the superior colliculus (SC) are essential for a variety of acute and persistent defensive responses to overhead looming stimuli. Optogenetic mapping revealed that SC projections to the lateral posterior nucleus (LP) of the thalamus, a non-canonical polymodal sensory relay, are sufficient to mimic visually evoked fear responses. In vivo electrophysiology experiments identified a di-synaptic circuit from SC through LP to the lateral amygdale (Amg), and lesions of the Amg blocked the full range of visually evoked defensive responses. Our results reveal a novel collicular?thalamic?Amg circuit important for innate defensive responses to visual threats. äProcessing of visually evoked innate fear by a non-canonical thalamic (epmc).pdf DeepDyve Pubget Overpricing