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10.1128/MMBR.00039-14 http://scihub22266oqcxt.onion/10.1128/MMBR.00039-14 C4402963!4402963!25652543     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microbiol+Mol+Biol+Rev 2015 ; 79 (1): 101-16 Nephropedia Template TP {{tp|p=25652543|t=2015. Origin and Proliferation of Multiple-Drug Resistance in Bacterial Pathogens |pdf=|usr=}}{{25652543}} gab.com Text Origin and Proliferation of Multiple-Drug Resistance in Bacterial Pathogens JO: Microbiol Mol Biol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25652543 #FOAvip Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because MDR infections are often significantly harder and more expensive to treat, they represent a growing public health threat. However, for different pathogens, different underlying mechanisms are traditionally used to explain these observations, and it is unclear whether each bacterial taxon has its own mechanism(s) for multidrug resistance or whether there are common mechanisms between distantly related pathogens. In this review, we provide a systematic overview of the causes of the excess of MDR infections and define testable predictions made by each hypothetical mechanism, including experimental, epidemiological, population genomic, and other tests of these hypotheses. Better understanding the cause(s) of the excess of MDR is the first step to rational design of more effective interventions to prevent the origin and/or proliferation of MDR. Twit Text FOAVip Origin and Proliferation of Multiple-Drug Resistance in Bacterial Pathogens ????Microbiol Mol Biol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25652543 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25652543 #FOAvip English Wikipedia <ref>{{Cite pmid|25652543}}</ref> Origin and Proliferation of Multiple-Drug Resistance in Bacterial Pathogens #MMPMID25652543 Chang HH; Cohen T; Grad YH; Hanage WP; O'Brien TF; Lipsitch M Microbiol Mol Biol Rev 2015[Mar]; 79 (1): 101-16 PMID25652543show ga Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because MDR infections are often significantly harder and more expensive to treat, they represent a growing public health threat. However, for different pathogens, different underlying mechanisms are traditionally used to explain these observations, and it is unclear whether each bacterial taxon has its own mechanism(s) for multidrug resistance or whether there are common mechanisms between distantly related pathogens. In this review, we provide a systematic overview of the causes of the excess of MDR infections and define testable predictions made by each hypothetical mechanism, including experimental, epidemiological, population genomic, and other tests of these hypotheses. Better understanding the cause(s) of the excess of MDR is the first step to rational design of more effective interventions to prevent the origin and/or proliferation of MDR. äOrigin and Proliferation of Multiple-Drug Resistance in Bacterial Path(epmc).pdf DeepDyve Pubget Overpricing