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10.1128/CMR.00124-14 http://scihub22266oqcxt.onion/10.1128/CMR.00124-14 C4402953!4402953 !25810419     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25810419 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Microbiol+Rev 2015 ; 28 (2 ): 523-39 Nephropedia Template TP {{tp|p=25810419 |t=2015. A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics |pdf=|usr=}}{{25810419 }} gab.com Text A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics JO: Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25810419 #FOAvip Tuberculosis (TB) is an ancient disease with an enormous global impact. Despite declining global incidence, the diagnosis, phenotyping, and epidemiological investigation of TB require significant clinical microbiology laboratory resources. Current methods for the detection and characterization of Mycobacterium tuberculosis consist of a series of laboratory tests varying in speed and performance, each of which yields incremental information about the disease. Since the sequencing of the first M. tuberculosis genome in 1998, genomic tools have aided in the diagnosis, treatment, and control of TB. Here we summarize genomics-based methods that are positioned to be introduced in the modern clinical TB laboratory, and we highlight how recent advances in genomics will improve the detection of antibiotic resistance-conferring mutations and the understanding of M. tuberculosis transmission dynamics and epidemiology. We imagine the future TB clinic as one that relies heavily on genomic interrogation of the M. tuberculosis isolate, allowing for more rapid diagnosis of TB and real-time monitoring of outbreak emergence. Twit Text FOAVip A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics ????Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25810419 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25810419 #FOAvip English Wikipedia <ref>{{Cite pmid|25810419 }}</ref> A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics #MMPMID25810419 Wlodarska M ; Johnston JC ; Gardy JL ; Tang P Clin Microbiol Rev 2015[Apr]; 28 (2 ): 523-39 PMID25810419 show ga Tuberculosis (TB) is an ancient disease with an enormous global impact. Despite declining global incidence, the diagnosis, phenotyping, and epidemiological investigation of TB require significant clinical microbiology laboratory resources. Current methods for the detection and characterization of Mycobacterium tuberculosis consist of a series of laboratory tests varying in speed and performance, each of which yields incremental information about the disease. Since the sequencing of the first M. tuberculosis genome in 1998, genomic tools have aided in the diagnosis, treatment, and control of TB. Here we summarize genomics-based methods that are positioned to be introduced in the modern clinical TB laboratory, and we highlight how recent advances in genomics will improve the detection of antibiotic resistance-conferring mutations and the understanding of M. tuberculosis transmission dynamics and epidemiology. We imagine the future TB clinic as one that relies heavily on genomic interrogation of the M. tuberculosis isolate, allowing for more rapid diagnosis of TB and real-time monitoring of outbreak emergence. |*Genomics [MESH] |Drug Resistance, Bacterial/genetics [MESH] |Host-Pathogen Interactions [MESH] |Humans [MESH] |Molecular Epidemiology [MESH] |Mutation/genetics [MESH] |Mycobacterium tuberculosis/*genetics [MESH]A microbiological revolution meets an ancient disease: improving the m(epmc).pdf DeepDyve Pubget Overpricing