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10.1002/mrm.24953 http://scihub22266oqcxt.onion/10.1002/mrm.24953 C4401079!4401079 !24302497     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24302497 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Magn+Reson+Med 2014 ; 72 (2 ): 471-6 Nephropedia Template TP {{tp|p=24302497 |t=2014. Imaging amide proton transfer and nuclear overhauser enhancement using chemical exchange rotation transfer (CERT) |pdf=|usr=}}{{24302497 }} gab.com Text Imaging amide proton transfer and nuclear overhauser enhancement using chemical exchange rotation transfer (CERT) JO: Magn Reson Med http://www.kidney.de/pget.php?&tw=1&pmid=24302497 #FOAvip PURPOSE: This study investigates amide proton transfer (APT) and nuclear overhauser enhancement (NOE) in phantoms and 9L tumors in rat brains at 9.4 Tesla, using a recently developed method that can isolate different contributions to exchange. METHODS: Chemical exchange rotation transfer (CERT) was used to quantify APT and NOEs through subtraction of signals acquired at two irradiation flip angles, but with the same average irradiation power. RESULTS: CERT separates and quantifies specific APT and NOE signals without contamination from other proton pools, and thus overcomes a key shortcoming of conventional CEST asymmetry approaches. CERT thus has increased specificity, though at the cost of decreased signal strength. In vivo experiments show that the APT effect acquired with CERT in 9L rat tumors (3.1%) is relatively greater than that in normal tissue (2.5%), which is consistent with previous CEST asymmetry analysis. The NOE effect centered at -1.6 ppm shows substantial image contrast within the tumor and between the tumor and the surrounding tissue, while the NOE effect centered at -3.5 ppm shows little contrast. CONCLUSION: CERT provides an image contrast that is more specific to chemical exchange than conventional APT by means of asymmetric CEST Z-spectra analysis. Twit Text FOAVip Imaging amide proton transfer and nuclear overhauser enhancement using chemical exchange rotation transfer (CERT) ????Magn Reson Med http://www.kidney.de/pget.php?&tw=1&pmid=24302497 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24302497 #FOAvip English Wikipedia <ref>{{Cite pmid|24302497 }}</ref> Imaging amide proton transfer and nuclear overhauser enhancement using chemical exchange rotation transfer (CERT) #MMPMID24302497 Zu Z ; Xu J ; Li H ; Chekmenev EY ; Quarles CC ; Does MD ; Gore JC ; Gochberg DF Magn Reson Med 2014[Aug]; 72 (2 ): 471-6 PMID24302497 show ga PURPOSE: This study investigates amide proton transfer (APT) and nuclear overhauser enhancement (NOE) in phantoms and 9L tumors in rat brains at 9.4 Tesla, using a recently developed method that can isolate different contributions to exchange. METHODS: Chemical exchange rotation transfer (CERT) was used to quantify APT and NOEs through subtraction of signals acquired at two irradiation flip angles, but with the same average irradiation power. RESULTS: CERT separates and quantifies specific APT and NOE signals without contamination from other proton pools, and thus overcomes a key shortcoming of conventional CEST asymmetry approaches. CERT thus has increased specificity, though at the cost of decreased signal strength. In vivo experiments show that the APT effect acquired with CERT in 9L rat tumors (3.1%) is relatively greater than that in normal tissue (2.5%), which is consistent with previous CEST asymmetry analysis. The NOE effect centered at -1.6 ppm shows substantial image contrast within the tumor and between the tumor and the surrounding tissue, while the NOE effect centered at -3.5 ppm shows little contrast. CONCLUSION: CERT provides an image contrast that is more specific to chemical exchange than conventional APT by means of asymmetric CEST Z-spectra analysis. |*Algorithms [MESH] |Amides/chemistry/metabolism [MESH] |Animals [MESH] |Brain Neoplasms/*metabolism [MESH] |Cell Line, Tumor [MESH] |Glioma/*metabolism [MESH] |Image Interpretation, Computer-Assisted/*methods [MESH] |Magnetic Resonance Imaging/*methods [MESH] |Magnetic Resonance Spectroscopy/*methods [MESH] |Protons [MESH] |Rats [MESH] |Rats, Sprague-Dawley [MESH] |Reproducibility of Results [MESH]Imaging amide proton transfer and nuclear overhauser enhancement using(epmc).pdf DeepDyve Pubget Overpricing