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10.1093/ckj/sfs048 http://scihub22266oqcxt.onion/10.1093/ckj/sfs048 C4400520!4400520!26069770     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Kidney+J 2012 ; 5 (3): 225-8 Nephropedia Template TP {{tp|p=26069770|t=2012. Azathioprine as successful maintenance therapy in IgG4-related tubulointerstitial nephritis |pdf=|usr=}}{{26069770}} gab.com Text Azathioprine as successful maintenance therapy in IgG4-related tubulointerstitial nephritis JO: Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=26069770 #FOAvip A 65-year-old man presented with a progressive increase in plasma creatinine (PCr). Two years before, diffusion-weighted magnetic resonance imaging had revealed a relapse of immunoglobulin G4 (IgG4)-related autoimmune pancreatitis (AIP) associated with sclerosing cholangitis. Bilateral hypointense renal cortical nodules were also described. Kidney biopsy showed patchy disappearance of tubules, sparse interstitial fibrosis and IgG4+ plasma cells (>30 per high power field) leading to the diagnosis of IgG4-related tubulointerstitial nephritis (TIN). Despite methylprednisolone, PCr and serum IgG4 levels remained elevated. Starting azathioprine (AZA) normalized IgG4 levels, which elicited corticosteroid withdrawal after 17 months. One year later, renal function remains stable. Our clinical observation underlines the importance of biological and radiological long-term follow-up of patients with previous AIP in order to early detect IgG4-related renal involvement. Corticosteroids are the first choice, but in the case of adverse effects or partial remission, AZA could be a useful and safe alternative therapy. Twit Text FOAVip Azathioprine as successful maintenance therapy in IgG4-related tubulointerstitial nephritis ????Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=26069770 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26069770 #FOAvip English Wikipedia <ref>{{Cite pmid|26069770}}</ref> Azathioprine as successful maintenance therapy in IgG4-related tubulointerstitial nephritis #MMPMID26069770 Pozdzik AA; Brochériou I; Demetter P; Matos C; Delhaye M; Devière J; Nortier JL Clin Kidney J 2012[Jun]; 5 (3): 225-8 PMID26069770show ga A 65-year-old man presented with a progressive increase in plasma creatinine (PCr). Two years before, diffusion-weighted magnetic resonance imaging had revealed a relapse of immunoglobulin G4 (IgG4)-related autoimmune pancreatitis (AIP) associated with sclerosing cholangitis. Bilateral hypointense renal cortical nodules were also described. Kidney biopsy showed patchy disappearance of tubules, sparse interstitial fibrosis and IgG4+ plasma cells (>30 per high power field) leading to the diagnosis of IgG4-related tubulointerstitial nephritis (TIN). Despite methylprednisolone, PCr and serum IgG4 levels remained elevated. Starting azathioprine (AZA) normalized IgG4 levels, which elicited corticosteroid withdrawal after 17 months. One year later, renal function remains stable. Our clinical observation underlines the importance of biological and radiological long-term follow-up of patients with previous AIP in order to early detect IgG4-related renal involvement. Corticosteroids are the first choice, but in the case of adverse effects or partial remission, AZA could be a useful and safe alternative therapy. äAzathioprine as successful maintenance therapy in IgG4-related tubuloi(epmc).pdf DeepDyve Pubget Overpricing