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10.1093/ckj/sfs031

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C4400509!4400509!26069775
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suck abstract from ncbi


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pmid26069775      Clin+Kidney+J 2012 ; 5 (3): 240-3
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  • Oncogenic osteomalacia illustrating the effect of fibroblast growth factor 23 on phosphate homeostasis #MMPMID26069775
  • Westerberg PA; Linde T; Vanderschueren D; Billen J; Jans I; Ljunggren Ö
  • Clin Kidney J 2012[Jun]; 5 (3): 240-3 PMID26069775show ga
  • In oncogenic osteomalacia (OOM), fibroblast growth factor 23 (FGF23) induces renal phosphate wasting and inhibits the appropriate increase of calcitriol. A patient suffering from OOM is described. Serum calcium, phosphate, biointact parathyroid hormone and intact FGF23 as well as the calcitriol and 24,25-vitamin D levels were measured before and after tumour removal. The clinical approach to a patient with hypophosphataemia is discussed and the changes in mineral metabolism after removal of a FGF23-producing tumour are described.
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