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10.1007/s00401-014-1308-9 http://scihub22266oqcxt.onion/10.1007/s00401-014-1308-9 C4399383!4399383!24916271     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Neuropathol 2014 ; 128 (4): 543-50 Nephropedia Template TP {{tp|p=24916271|t=2014. A comparison of A? amyloid pathology staging systems and correlation with clinical diagnosis |pdf=|usr=}}{{24916271}} gab.com Text A comparison of A amyloid pathology staging systems and correlation with clinical diagnosis JO: Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=24916271 #FOAvip Current neuropathological Alzheimer's disease (AD) criteria from the National Institute on Aging-Alzheimer's Association (NIA-AA) incorporate two staging systems for A? pathology, namely the Thal A? phase (TAP) and the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) methods. The goal of this study was to compare and contrast results obtained with these two different staging systems for A? pathology since this is critical for future correlations of A? amyloid imaging data with A? neuropathology data based on immunohistochemical detection of A? deposits. A total of 123 cases, divided into 82 training and 41 validation cases, with a diagnosis of either unremarkable adult brain (normal) or AD and CERAD scores ranging from none to frequent were included. There was no clear and consistent relationship between CERAD and the TAP A? scores with the exception of scores for the highest plaque burdens (i.e., CERAD C3 and TAP A3) in the cases studied here. However, we developed an algorithm that relates CERAD scores to TAP scores with high agreement (94 % in training and 98 % in the validation set). In addition, TAP scores were a better predictor of dementia (sensitivity of 94 % specifcity 87.7 %) than CERAD scores (sensitivity of 57 % specifcity 100 %). Yet, further research is needed to define strategies to relate CERAD and TAP A? plaque scores to compare their utility and for determining the clinical associations of these different amyloid staging systems with aging and AD. Twit Text FOAVip A comparison of A amyloid pathology staging systems and correlation with clinical diagnosis ????Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=24916271 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24916271 #FOAvip English Wikipedia <ref>{{Cite pmid|24916271}}</ref> A comparison of A? amyloid pathology staging systems and correlation with clinical diagnosis #MMPMID24916271 Boluda S; Toledo JB; Irwin DJ; Raible KM; Byrne MD; Lee EB; Lee VMY; Trojanowski JQ Acta Neuropathol 2014[Oct]; 128 (4): 543-50 PMID24916271show ga Current neuropathological Alzheimer's disease (AD) criteria from the National Institute on Aging-Alzheimer's Association (NIA-AA) incorporate two staging systems for A? pathology, namely the Thal A? phase (TAP) and the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) methods. The goal of this study was to compare and contrast results obtained with these two different staging systems for A? pathology since this is critical for future correlations of A? amyloid imaging data with A? neuropathology data based on immunohistochemical detection of A? deposits. A total of 123 cases, divided into 82 training and 41 validation cases, with a diagnosis of either unremarkable adult brain (normal) or AD and CERAD scores ranging from none to frequent were included. There was no clear and consistent relationship between CERAD and the TAP A? scores with the exception of scores for the highest plaque burdens (i.e., CERAD C3 and TAP A3) in the cases studied here. However, we developed an algorithm that relates CERAD scores to TAP scores with high agreement (94 % in training and 98 % in the validation set). In addition, TAP scores were a better predictor of dementia (sensitivity of 94 % specifcity 87.7 %) than CERAD scores (sensitivity of 57 % specifcity 100 %). Yet, further research is needed to define strategies to relate CERAD and TAP A? plaque scores to compare their utility and for determining the clinical associations of these different amyloid staging systems with aging and AD. äA comparison of A? amyloid pathology staging systems and correlation w(epmc).pdf DeepDyve Pubget Overpricing