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10.1126/science.1258100 http://scihub22266oqcxt.onion/10.1126/science.1258100 C4398891!4398891!25431489     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Science 2015 ; 347 (6219): 269-73 Nephropedia Template TP {{tp|p=25431489|t=2015. Interferon ? cures persistent murine norovirus infection in the absence of adaptive immunity |pdf=|usr=}}{{25431489}} gab.com Text Interferon cures persistent murine norovirus infection in the absence of adaptive immunity JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=25431489 #FOAvip Norovirus gastroenteritis is a major public health burden worldwide. Although fecal shedding is important for transmission of enteric viruses, little is known about the immune factors that restrict persistent enteric infection. We report here that while the cytokines interferon-? (IFN-?) and IFN-? prevented the systemic spread of murine norovirus (MNoV), only IFN-? controlled persistent enteric infection. Infection-dependent induction of IFN-? was governed by the MNoV capsid protein and correlated with diminished enteric persistence. Treatment of established infection with IFN-? cured mice in a manner requiring non-hematopoietic cell expression of the IFN-? receptor, Ifnlr1, and independent of adaptive immunity. These results suggest the therapeutic potential of IFN-? for curing virus infections in the gastrointestinal tract. Twit Text FOAVip Interferon cures persistent murine norovirus infection in the absence of adaptive immunity ????Science http://www.kidney.de/pget.php?&tw=1&pmid=25431489 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25431489 #FOAvip English Wikipedia <ref>{{Cite pmid|25431489}}</ref> Interferon ? cures persistent murine norovirus infection in the absence of adaptive immunity #MMPMID25431489 Nice TJ; Baldridge MT; McCune BT; Norman JM; Lazear HM; Artyomov M; Diamond MS; Virgin HW Science 2015[Jan]; 347 (6219): 269-73 PMID25431489show ga Norovirus gastroenteritis is a major public health burden worldwide. Although fecal shedding is important for transmission of enteric viruses, little is known about the immune factors that restrict persistent enteric infection. We report here that while the cytokines interferon-? (IFN-?) and IFN-? prevented the systemic spread of murine norovirus (MNoV), only IFN-? controlled persistent enteric infection. Infection-dependent induction of IFN-? was governed by the MNoV capsid protein and correlated with diminished enteric persistence. Treatment of established infection with IFN-? cured mice in a manner requiring non-hematopoietic cell expression of the IFN-? receptor, Ifnlr1, and independent of adaptive immunity. These results suggest the therapeutic potential of IFN-? for curing virus infections in the gastrointestinal tract. äInterferon ? cures persistent murine norovirus infection in the absenc(epmc).pdf DeepDyve Pubget Overpricing