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10.1002/wnan.1308 http://scihub22266oqcxt.onion/10.1002/wnan.1308 C4397116!4397116!25346461     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Wiley+Interdiscip+Rev+Nanomed+Nanobiotechnol 2015 ; 7 (3): 298-314 Nephropedia Template TP {{tp|p=25346461|t=2015. Learning from Biology: Synthetic Lipoproteins for Drug Delivery |pdf=|usr=}}{{25346461}} gab.com Text Learning from Biology: Synthetic Lipoproteins for Drug Delivery JO: Wiley Interdiscip Rev Nanomed Nanobiotechnol http://www.kidney.de/pget.php?&tw=1&pmid=25346461 #FOAvip Synthetic lipoproteins represent a relevant tool for targeted delivery of biological/chemical agents (chemotherapeutics, siRNAs, photosensitizers and imaging contrast agents) into various cell types. These nanoparticles offer a number of advantages on drugs delivery over their native counterparts while retaining their natural characteristics and biological functions. Their ultra-small size (<30nm), high biocompatibility, favorable circulation half-life and natural ability to bind specific lipoprotein receptors i.e. low-density lipoprotein receptor (LDLR) and Scavenger receptor class B member 1 (SRB1) that are found in a number of pathological conditions (e.g. cancer, atherosclerosis), make them superior delivery strategies when compared to other nanoparticle systems. We review the various approaches that have been developed for the generation of synthetic lipoproteins and their respective applications in vitro and in vivo. More specifically, we summarize the way to address the limitation on use of reconstituted lipoproteins by means of natural or recombinant apolipoproteins, as well as apolipoprotein mimetic molecules. Finally, we provide an overview of the advantages and disadvantages of these approaches and discuss future perspectives for clinical translation of these nanoparticles. Twit Text FOAVip Learning from Biology: Synthetic Lipoproteins for Drug Delivery ????Wiley Interdiscip Rev Nanomed Nanobiotechnol http://www.kidney.de/pget.php?&tw=1&pmid=25346461 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25346461 #FOAvip English Wikipedia <ref>{{Cite pmid|25346461}}</ref> Learning from Biology: Synthetic Lipoproteins for Drug Delivery #MMPMID25346461 Huang H; Cruz W; Chen J; Zheng G Wiley Interdiscip Rev Nanomed Nanobiotechnol 2015[May]; 7 (3): 298-314 PMID25346461show ga Synthetic lipoproteins represent a relevant tool for targeted delivery of biological/chemical agents (chemotherapeutics, siRNAs, photosensitizers and imaging contrast agents) into various cell types. These nanoparticles offer a number of advantages on drugs delivery over their native counterparts while retaining their natural characteristics and biological functions. Their ultra-small size (<30nm), high biocompatibility, favorable circulation half-life and natural ability to bind specific lipoprotein receptors i.e. low-density lipoprotein receptor (LDLR) and Scavenger receptor class B member 1 (SRB1) that are found in a number of pathological conditions (e.g. cancer, atherosclerosis), make them superior delivery strategies when compared to other nanoparticle systems. We review the various approaches that have been developed for the generation of synthetic lipoproteins and their respective applications in vitro and in vivo. More specifically, we summarize the way to address the limitation on use of reconstituted lipoproteins by means of natural or recombinant apolipoproteins, as well as apolipoprotein mimetic molecules. Finally, we provide an overview of the advantages and disadvantages of these approaches and discuss future perspectives for clinical translation of these nanoparticles. äLearning from Biology: Synthetic Lipoproteins for Drug Delivery (epmc).pdf DeepDyve Pubget Overpricing